87810-56-8
87810-56-8 结构式
基本信息
中文别名
磷三烯菌素 英文别名
CL-1565AAntibiotic CI-920
Antibiotic CL-1565A
Phosphotrienin, CI 920, CL 1565A, PD 110161, NSC 339638
(6R)-5,6-Dihydro-6-[(1E,3R,4R,6R,7Z,9Z,11E)-3,6,13-trihydroxy-3-methyl-4-phosphonooxy-1,7,9,11-tridecatetrenyl]-2H-pyran-2-one
应用领域
用途一
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The antitumour potential of fostriecin has attracted considerable interest, focused on its mode of action as a topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein phosphatase PP2A.