| Identification | Back Directory | [Name]
4-[2,2-bis[(p-tolylsulfonyl)-methyl]acetyl]benzoic acid-N-hydroxy succinimidyl ester | [CAS]
899452-51-8 | [Synonyms]
Bis-sulfone SE
Bis–sulfone NHS Ester
2,5-Dioxopyrrolidin-1-yl 4-(3-tosyl-2-(tosylmethyl)propanoyl)benzoate
4-[2,2-bis[(p-tolylsulfonyl)-methyl]acetyl]benzoic acid-N-hydroxy succinimidyl ester | [Molecular Formula]
C29H27NO9S2 | [MDL Number]
MFCD30458024 | [MOL File]
899452-51-8.mol | [Molecular Weight]
597.66 |
| Hazard Information | Back Directory | [Description]
Bis-sulfone NHS Ester is a bis-alkylating labeling reagent that is selective for the cysteine sulfur atoms from a native disulfide. These reagents undergo bis-alkylation to conjugate both thiols derived from the two cysteine residues of a reduced native disulfide bond such as the interchain disulfide bonds of an antibody. The reaction results in covalent rebridging of the disulfide bond via a three carbon bridge leaving the protein structurally intact. |
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| Company Name: |
Tcichem, Inc.
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| Tel: |
13918644899 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList19113/0.htm |
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