| Identification | Back Directory | [Name]
Shellac | [CAS]
9000-59-3 | [Synonyms]
Lacca
Shellac
Gum lac
Molumba
Opaglos
seedlac
Sllellac
SHELLACS
Schellack
Waxshellac
Citrus gleam
Shellac Flake
SHELLAC ORANGE
WaxvonSchellack
Shellag。Bleached
Hodgsons Shellac
Shellac, Bleached
Shellac:waxyshellac
SHELLAC GUM, ORANGE
Shellac wax-free,Lacca
Resins, lac or shellac
SHELLAC WAX-FREE, PH EUR
SHELLAC ORANGE BEST QUALITY
Shellac:dewaxedgarnetshellac
Shellac:dewaxedorangeshellac
Shellac:dewaxeddecolorisedshellac
Shellac:dewaxedbleachedshellacpowder | [EINECS(EC#)]
232-549-9 | [Molecular Formula]
unspecified | [MDL Number]
MFCD00148309 |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
115-120° | [density ]
1.035-1.140 | [storage temp. ]
2-8°C | [solubility ]
Practically insoluble in water, gives a more or less opalescent solution (wax containing shellac and bleached shellac) or a clear solution (dewaxed shellac and bleached, dewaxed shellac) in anhydrous ethanol. When warmed it is sparingly soluble or soluble in alkaline solutions. | [Odor]
mild woody | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Dielectric constant]
2.0（Ambient） | [CAS DataBase Reference]
9000-59-3 | [EPA Substance Registry System]
Shellac(9000-59-3) |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Uses]
Chiefly in lacquers and varnishes; also in manufacture of buttons, grinding wheels, sealing wax, cements, inks, phonograph records, paper; for stiffening hats; in electrical machines; coating confections and medicinal tablets; finishing leather. | [Hazard]
(Alcohol solution) Flammable, dangerous
fire risk. | [Definition]
shellac: A hard resin produced as asecretion by a plant parasite, thesouth-east Asian lac insect Laciferlacca. It is used in sealing wax, varnish(French polish), and electrical insulators. | [Production Methods]
Shellac or lac is cultivated and refined from lacca, a resinous
secretion produced by the tiny insect Kerria lacca (Kerr) Lindinger
(Coccideae), formerly Laccifer lacca (Kerr). The insects are parasitic
on certain trees, mainly in India. In Thailand and South China, the
resin is secreted by another species, Laccifer chinensis (Madihassan)
on different trees. The insects pierce through the bark of the tree
and transform the sap into a natural polyester resin, called stick lac,which is secreted through the surface of their body. The resin forms
thick encrustations on the smaller branches and twigs, which are
then scraped off the twigs and further processed to produce seed lac,
as it is known at this stage. Seed lac is then refined to become
shellac.
The chemical composition, properties and the color of shellac
depend on the insect or insect strain, and thus the host tree, as well
as the process used for refining. Three very different processes are
used for refining the seed lac to shellac (bleaching, melting, and
solvent extraction), resulting in products with different characteristics
and properties.
Bleaching process Refined bleached or white shellac is obtained
by dissolving seed lac in an aqueous alkaline solution, which is
then filtered, dewaxed, and bleached with sodium hypochlorite
to completely remove the color. However, changes in the
molecular structure and the addition of chlorine substituents
may lead to self-crosslinking and polymerization.
Melting process After melting the seed lac, the highly viscous
molten lac is pressed through a filter and drawn to a thin film.
Once cooled, the film breaks into thin flakes. The shellac wax is
not removed by this process and the color depends on the type of
seed lac used.
Solvent extraction process Solvent extraction is a very gentle
process for refining shellac. The seed lac is dissolved in ethanol,
and wax and impurities are removed by filtration. Activated
carbon is used to produce light-colored grades. After a further
filtration step and the removal of ethanol, the resin is drawn to a
thin film, which breaks into flakes after cooling. The properties
of the final product depend on the type of seed lac used and are
influenced by the processing parameters and the grade of
activated carbon.
PhEur 6.2 and USP32–NF27 define four types of shellac
depending on the refining method, and the JP XV mentions two
types.
The use of the term ‘pharmaceutical grade’ as well as the quality
of the shellac depends on the manufacturer.
Seed lac is mainly produced in India, Thailand and China.
Orange shellac, refined by the melting process, is manufactured by
several companies in India, Thailand and South-East Asia. Bleached
shellac is produced in the USA, Canada, Japan, India, Thailand and
South China. Dewaxed orange shellac is refined by the solvent
extraction process in Germany, Japan and India. | [Pharmaceutical Applications]
Shellac is widely used as a moisture barrier coating for tablets and
pellets due to its low water vapor and oxygen permeability. It has
usually been applied in the form of alcoholic or aqueous solutions
(pharmaceutical glazes). However, due to stability problems with
alcoholic shellac solutions, it has had limited use in the pharmaceutical
industry for modified-release or enteric coatings.
Shellac, particularly novel aqueous shellac solutions, is mainly
used in food products and nutritional supplements. Recent research
results indicate good application properties and chemical stability
of shellac films from aqueous shellac solutions. Aqueous
ammonium shellac solutions, based on dewaxed orange shellac,
do not show the problems exhibited by alcoholic shellac solutions
and are used as an enteric coating for pellets, tablets, soft and hard
gelatine capsules, primarily in nutritional supplements.
Shellac is a primary ingredient of pharmaceutical printing inks
for capsules and tablets, and can be applied as a 40% w/v alcoholic
solution. It has also been used to apply one or two sealing coats to
tablet cores to protect them from moisture before being film- or
sugar-coated.
Other applications of shellac are the coating or encapsulation of
powders or granules, e.g. in probiotics. Prior to the introduction of
film coating, a combination of shellac, cetostearyl alcohol and
stearic acid was used as an enteric coating. In cosmetics, shellac is
used in hairsprays, mascara and lipstick formulations. Aqueous
shellac solutions are also used for colonic drug delivery. | [Safety]
Shellac is used in oral pharmaceutical formulations, food products,
and cosmetics. It is generally regarded as an essentially nonirritant
and nontoxic material at the levels employed as an excipient. | [storage]
After long periods of storage, shellac becomes less readily soluble in
alcohol, less fluid on heating, and darker in color.
Shellac should be stored in a well-closed container at temperatures
below 15°C. Wax-containing grades should be mixed before
use to ensure uniform distribution of the wax. Orange and dewaxed
orange shellac have a shelf-life of 1 to 2 years. The shelf-life of
bleached shellac is approximately 6 months. | [Incompatibilities]
Shellac is chemically reactive with aqueous alkalis, organic bases,
alcohols, and agents that esterify carboxyl groups. Therefore,
shellac should be used with caution in the presence of such
compounds. | [Regulatory Status]
Accepted as a food additive in the USA, Europe, and Japan.
Included in the FDA Inactive Ingredients Database (oral capsules
and tablets). Included in nonparenteral medicines (oral tablets and
capsules, often in printing ink formulations) licensed in the UK.
Included in the Canadian List of Acceptable Non-medicinal
Ingredients. |
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