ChemicalBook--->CAS DataBase List--->9001-31-4

9001-31-4

9001-31-4 Structure

9001-31-4 Structure
IdentificationBack Directory
[Name]

FIBRIN
[CAS]

9001-31-4
[Synonyms]

FIBRIN
Fibrins
FIBRIN,BLOOD
BLOOD FIBRIN
FIBRIN BOVINE
Fibrin human blood
fibrin from human plasma
FIBRIN, FROM BOVINE BLOOD
Fibrin from porcine plasma
fibrin washed from pig plasma
fibrin washed from bovine blood
fibrin washed from human plasma
2-(glycylamino)-N-methyl-acetamide
2-[(2-aminoacetyl)amino]-N-methylacetamide
2-(2-azanylethanoylamino)-N-methyl-ethanamide
[EINECS(EC#)]

232-597-0
[Molecular Formula]

C5H11N3O2
[MDL Number]

MFCD00131058
[MOL File]

9001-31-4.mol
[Molecular Weight]

145.16
Chemical PropertiesBack Directory
[Definition]

An insoluble blood protein resulting from the hydrolysis of fibrinogen by the action of thrombin; it polymerizes to form blood clots. Recent research has found that it forms a protective coating on tumors that inhibits antigenic activity, thus protecting
[form ]

Solid
[color ]

White to yellow
[InChIKey]

BWGVNKXGVNDBDI-UHFFFAOYSA-N
Safety DataBack Directory
[Hazard Codes ]

B
[Safety Statements ]

22-24/25
[WGK Germany ]

3
Hazard InformationBack Directory
[Uses]

Fibrin is transformed from fibrinogen by thrombin. It has been used in studies to obtain fibrin specific monoclonal antibodies (mAbs). These mAbs may then be used to determine their role on fibrin polymerization and use in fibrin quatification in blood plasma.
[Agricultural Uses]

Fibrin is an insoluble fibrous protein that causes blood to clot. Fibrinogen, a protein synthesized in the liver, dissolves in the blood and circulates in the body. Fibrinogen is converted to fibrin by the enzyme thrombin which builds up a spongy, fibrous network joining the edges of the wound to effect clotting and prevent bleeding. Thus, thrombin is responsible for the formation of fibrin (from the soluble fibrinogen) which forms the fibrous network, thus trapping the blood cells during an injury.
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