ChemicalBook--->CAS DataBase List--->9001-47-2

9001-47-2

9001-47-2 Structure

9001-47-2 Structure
IdentificationBack Directory
[Name]

GLUTAMINASE
[CAS]

9001-47-2
[Synonyms]

EC 3.5.1.2
GLUTAMINASE
l-glutaminas
l-glutaminase
Glutaminase F
GLUTAMINASE USP/EP/BP
glutamineaminohydrolase
glutaminase from E. coli
L-GLUTAMINE AMIDOHYDROLASE
glutaminase from escherichia coli
Glutaminase from Bacillus subtilis
Glutaminasefrombacillussubtilis50ug
Native Escherichia coli Glutaminase
glutaminase grade V from escherichia*coli
glutaminase grade ii from escherichia*coli
glutaminase grade vii from escherichia*coli
[EINECS(EC#)]

618-332-5
[MDL Number]

MFCD00131193
Chemical PropertiesBack Directory
[storage temp. ]

−20°C
[form ]

lyophilized powder
[color ]

Off-white to light yellow
Safety DataBack Directory
[Symbol(GHS) ]


GHS08
[Signal word ]

Danger
[Hazard statements ]

H334
[Precautionary statements ]

P261-P285-P304+P341-P342+P311-P501
[Safety Statements ]

22-24/25
[WGK Germany ]

1
[RTECS ]

MA2275050
[F ]

3-10
Hazard InformationBack Directory
[Uses]

Glutaminase from E.coli has been used:
  • for the determination of glutamine from the cerebral cortex tissue extract
  • for immobilization on aminopropylsilylated controlled pore glass (CPG) for determination of glutamine
  • in combination with acivicin in in vitro melanoma cells and MCF-7 and OAW-42 cells for cell proliferation and invasiveness assay.

[General Description]

Glutaminase is an amidohydrolase. It has the catalytic domain in the N-terminal and the C-terminal extension possesses STAS domain.
[Biochem/physiol Actions]

Glutaminase from Escherichia coli along with acivicin, a glutamine analog regulates proliferation and invasiveness of cancer cells. Bacterial glutaminase is implicated in increasing the life span of cancer patients by lowering the tumor burden.
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