ChemicalBook--->CAS DataBase List--->9002-61-3

9002-61-3

9002-61-3 Structure

9002-61-3 Structure
IdentificationBack Directory
[Name]

Chorionic gonadotrophin
[CAS]

9002-61-3
[Synonyms]

HCG
apl
HGG
LHA
TSHA
HUCG
gonan
physex
riogon
praedyn
pregnyl
profasi
gonadex
ambinon
chorulon
apoidina
choragon
chorigon
predalon
gravimun
korotrin
gonabion
randonos
pregnesin
lutormone
physostab
coriantin
follutein
endocorion
ferti-cept
antelobine
antophysin
antuitrins
HCG, HUMAN
primogonyl
synaphorin
Aids072611
Aids-072611
HCG, INTACT
anteparsine
choriogonin
apl(hormone)
apl[hormone]
prolan(bayer)
glanduantin-ch
gonadotraphonlh
gonadyl-chorionic
Choriogonin, HCG
choriogonadotropin
pregnancyurineextract
gonadotropin,chorionic
Choriogonadotropinalfa
chorionicgonadotrophin
CHORIONIC GONADOTROPIN
pregnancyurine hormone
beta chorionic gonadotropin
gonadotropin,humanchorionic
CHORIONIC GONADOTROPIN-ALPHA
HUMAN CHORIONIC GONADOTROPIN
CHORIONIC GONADOTROPIN HORSE
CHORIONIC GONADOTROPIN HUMAN
chorionicgonadotropichormone
HUMAN CHORIONIC GONADOTROPHIN
Humanchrorionicgonadotrophine
gonadotrop(h)in,humanchorionic
CHORIONIC GONADOTROPIN, U.S.P.
Chorionic gonadotropin huMan (HCG)
CHORIONIC GONADOTROPIN, HUMAN URINE
CHORIONIC GONADOTROPHIN, HUMAN, INTACT
CHORIONIC GONADOTROPIN HUMAN RECOMBINAN&
CHORIONIC GONADOTROPIN FROM HUMAN &
CHORIONIC GONADOTROPIN HUMAN,EMBRYO TEST ED
CHORIONIC GONADOTROPHIN, HUMAN URINE, INTACT
Chorionic gonadotropin human,Choriogonin, HCG
Chorionic Gonadotropin, HumanUrine, Iodination Grade
PURIFIEDHCG(CHORIONICGONADOTROPINFROMHUMAN*PREGNANCYURINE)
CHORIONIC GONADOTROPIN (HCG)DEVELOPED IN RABBIT (3,500 IU/MG)
Human Chorionic Gonadotropin (1 vial, 5,760 USP Units per package)
Human Chorionic Gonadotropin (1 vial, 5,760 USP Units per package) (COLD SHIPMENT REQUIRED)
[EINECS(EC#)]

232-660-2
[Molecular Formula]

C17H28
[MDL Number]

MFCD00130797
[MOL File]

9002-61-3.mol
[Molecular Weight]

232.404
Chemical PropertiesBack Directory
[Appearance]

White or yellowish-white, amorphous powder.
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble1ML/vial
[form ]

lyophilized powder
[color ]

White to off-white
Safety DataBack Directory
[Hazard Codes ]

B,Xn
[Risk Statements ]

63-62
[Safety Statements ]

22-36-36/37
[WGK Germany ]

3
[RTECS ]

MD6953000
[HS Code ]

2937190000
[Hazardous Substances Data]

9002-61-3(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Ethanol-->Sodium chloride-->Sodium acetate trihydrate-->Ammonium sulfate-->Acetamide-->Benzoic acid-->Aluminium potassium sulfate dodecahydrate-->Calcium acetate-->Trisodium phosphate-->TRIS BORATE EDTA BUFFER, 10X, DNASE, RNASE AND PROTEASE FREE, PH 8.3, FOR MOLECULAR BIOLOGY-->ACETALDEHYDE AMMONIA-->HEMOGLOBIN-->IGE, ANTI-HUMAN, GOAT, IGG FRAC, FITC, LQ-->Ethacridine lactate monohydrate
Hazard InformationBack Directory
[Chemical Properties]

White or yellowish-white, amorphous powder.
[Uses]

Gonad-stimulating principle.
[Application]

Human chorionic gonadotropin (hCG) is a chemical produced by the trophoblast tissue, which is usually present in the early embryo and will eventually become part of the placenta. Measuring hCG levels helps to identify normal, pathological and miscarried pregnancies. Measuring hCG is also beneficial for many cancers including choriocarcinoma and extrauterine malignancies.
[Production Methods]

CG is produced in the chorion.
[Brand name]

A.P.L. (Ferring Pharmaceuticals); Follutein (Bristol-Myers Squibb); Pregnyl (Organon).
[General Description]

Glycoprotein hormone consisting of a 92-amino acid α-chain which is identical to that of LH, FSH, and TSH; and a distinct 149-amino acid β-chain. Produced by chorionic tissue and responsible for maintaining the corpus luteum during early pregnancy. Also produced by trophoblast cell neoplasms, which are marked by elevated free hCG β-chains and hyperglycosylated hCG.
[Biochem/physiol Actions]

Elevated levels of hCG is observed in trophoblastic cancer. hCG levels are indicators of pregnancy and β subunit is majorly present in urine samples. hCG isoform detection is useful in the diagnosis and management of trophoblastic related diseases including carcinomas.
[Clinical Use]

Choriogonadotropin alfa is obtained by rDNA technology and is biologically and chemically identical to hCG of natural origin. It is used, like hCG of natural origin, for inducing ovulation in women with anovulatory infertility. Following proper pretreatment with a GnRH antagonist or superagonist to desensitize the pituitary, women participating in ART are treated with a folliclestimulating agent (e.g., menotropins) to effect the final maturation of the follicles within the ovaries. Ultrasonograms are used to determine proper follicle maturation before the administration of choriogonadotropin alfa to induce ovulation. A distinct advantage of this product is that it can be self-administered by the patient via SC injection.
[Veterinary Drugs and Treatments]

The veterinary product’s labeled indication is for “parenteral use in cows for the treatment of nymphomania (frequent or constant heat) due to cystic ovaries.” It has been used for other purposes in several species; refer to the Dosage section for more information.
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