ChemicalBook--->CAS DataBase List--->9012-33-3

9012-33-3

9012-33-3 Structure

9012-33-3 Structure
IdentificationBack Directory
[Name]

β-N-AcetylglucosaMinidase
[CAS]

9012-33-3
[Synonyms]

NAG
NAGLU
MPS3B
MPS-IIIB
EC 3.2.1.30
EC 3.2.1.52
β-N-acetylhexosaminidase
β-N-AcetylglucosaMinidase
Acetylglucosaminidase, B2
B-N-ACETYLGLUCOSAMINIDASE P
BETA-N-ACETYLHEXOSAMINIDASE
Acetylglucosaminidase, beta-
BETA-N-ACETYLGLUCOSAMINIDASE
Acetylhexosaminidase, .beta.-
BETA-N-ACETYLGLUCOSAMINIDASE H
N-ACETYL-BETA-D-GLUCOSAMINIDASE
Achromopeptidase Lysobacter sp.
β1-2,3,4,6-N-Acetylglucosaminidase,
BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE
Native Human β-N-Acetylglucosaminidase
Native Bovine β-N-Acetylglucosaminidase
B-N-ACETYLGLUCOSAMINIDASE FROM JACK BEANS
B-N-ACETYLGLUCOSAMINIDASE FROM BOVINEKID NEY
β-n-acetylglucosaminidase from bovine kidney
β-n-acetylglucosaminidase from human placenta
B-N-ACETYLGLUCOSAMINIDASEFROM HUMAN PLAC ENTA
B-N-ACETYLGLUCOSAMINIDASE AFROM HUMAN PL ACENTA
beta-N-Acetylglucosaminidase from bovine kidney
B-N-ACETYLGLUCOSAMINIDASE FROMASPERGILLU S NIGER
B-N-ACETYLGLUCOSAMINIDASE AFROM PORCINE PLACENTA
B-N-ACETYLGLUCOSAMINIDASE, RECOMBINANT, EXPRESSED I
β-N-AcetylglucosaminidaseA from bovine epididymis
β-N-AcetylglucosaminidaseB from bovine epididymis
Native Canavalia ensiformis β-N-Acetylglucosaminidase
β-n-acetylglucosaminidase from streptococcus pneumoniae
N-ACETYL-BETA-D-GLYCOSAMINIDE-N-ACETYLGLUCOSAMINOHYDROLASE
Hexosaminidase 3A from Thermotoga neapolitana, Recombinant
beta-N-Acetylglucosaminidase from Streptococcus pneumoniae
BETA-N-ACETYLGLUCOSAMINIDASE,JACK BEANS, ~50 U/MG, 500 UG*
β-N-Acetylglucosaminidase P preparation from human placenta
β-N-Acetylglucosaminidase A preparation from human placenta
Hexosaminidase 3C from Saccharophagus degradans, Recombinant
β-N-Acetylglucosaminidase A preparation from porcine placenta
β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution
β-n-acetylglucosaminidase from canavalia ensiformis (jack bean)
2-Acetamido-2-deoxy-β-D-glucoside acetamidodeoxyglucohydrolase
BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, STREPTOCOCCUS PNEUMONIAE
β-N-Acetylglucosaminidase preparation from Aspergillus niger
BETA1-2,3,4,6-N-ACETYLGLUCOSAMINIDASE, S. PNEUMONIAE, RECOMBINANT
2-ACETAMIDO-2-DEOXY-BETA-D-GLUCOSIDE ACETAMIDODEOXYGLUCOHYDROLASE
β-N-Acetylhexosaminidase from Streptococcus pyogenes, Recombinant
beta-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean)
β-N-Acetylglucosaminidase from Streptococcus pneumoniae, Recombinant
β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase
β1-2,3,4,6-N-Acetylglucosaminidase, Streptococcus pneumoniae, Recombinant, E. coli
β-N-Acetylhexosaminidase, β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase solution
β-N-Acetylglucosaminidase from Canavalia ensiformis (Jack bean),β-N-Acetyl-D-hexosaminide N-acetylhexosaminohydrolase, β-N-Acetylhexosaminidase
[EINECS(EC#)]

232-730-2
[Molecular Formula]

NULL
[MDL Number]

MFCD00081402
Chemical PropertiesBack Directory
[density ]

1.37[at 20℃]
[vapor pressure ]

0.004Pa at 25℃
[storage temp. ]

2-8°C
[form ]

lyophilized powder
[color ]

Colorless to light yellow
[Water Solubility ]

125g/L at 25℃
[LogP]

-1.3 at 20℃
Safety DataBack Directory
[Hazard Codes ]

B
[Risk Statements ]

20/22-24-37/38-41-42
[Safety Statements ]

53-26-36/37/39-45
[WGK Germany ]

3
[F ]

10
Hazard InformationBack Directory
[Uses]

Bovine kidney β-N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer′s Disease .
[Uses]

β -N-acetylglucosaminidase is a lysosomal enzyme used to hydrolyze N-acetyl-β-D-glucosaminides and N-acetyl-β-Dgalactosaminides. It is used in chemoenzymatic synthesis of oligosaccharides based on their effective transglycosylation of β-GlcNAc and β-GalNAcc. It may be a useful tool to study Alzheimer’s Disease 1 . Acetylglucosaminidase from Canavalia ensiformis has been used to study enzymic detachment of biofilms.
[Flammability and Explosibility]

Notclassified
[Biochem/physiol Actions]

β-N-Acetylglucosaminidase from Streptococcus pneumoniae is an extracellular glycosidase and has broad specificity over the β1-3 and β1-6 linkages present in mucins. It belongs to the glycoside hydrolase family 85 (GH85). Also called endo-β-N-acetylglucosaminidase, it cleaves at the asparagine residue of the di-N-acetylchitobiose structure in oligosaccharides and acts on fucosylated N-glycan core. Its deglycosylation functionality is exploited in studying functions of glycoproteins.
[Purification Methods]

Purify it by chromatography on DEAD-Biogel, hydroxylapatite chromatography and gel filtration through Sephacryl S200. Two isoforms: a hexosaminidase EI with Km 177WM
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