| Identification | Back Directory | [Name]
APOFERRITIN | [CAS]
9013-31-4 | [Synonyms]
APOFERRITIN
FERRITIN, APO-, EQUINE
Ferritins, apoferritins
APOFERRITIN, HORSE SPLEEN
APOFERRITIN FROM HORSE SPLEEN
FERRITIN, APO-, EQUINE SPLEEN
Native Equine Spleen Apoferritin
Apoferritin from equine spleen
APOFERRITIN,HORSE SPLEEN,FOR GEL FILTRAT ION CHROMA | [Molecular Formula]
NULL | [MDL Number]
MFCD00081365 |
| Hazard Information | Back Directory | [Uses]
Apoferritin from equine spleen has been used:
- to determine its partition coefficients in phase systems
- in NaCl for iron loading of cultured cells
- in in situ liquid scanning transmission electron microscope for imaging the interface of biology and nanotechnology
| [Uses]
Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin IX. | [Uses]
Apoferritin is a gel filtration molecular weight marker that can be used in gel filtration chromatography and protein chromatography. Apoferritin has the ability to demetallate hemin and to metallate protoporphyrin. Apoferritin is used as a novel nanocarrier to load methylene blue (MB) and demonstrate its potential applications for photodynamic therapy of cancer. | [Biochem/physiol Actions]
This protein shell of ferritin lacking iron is widely used for the calibration of gel filtration columns and sodium dodecyl sulfate (SDS)-polyacrylamide gel electrophoresis. It is very abundant in beta-cells of the pancreas where it acts as an anti-oxidant. When added to cultured endothelial cells apoferritin is taken up in a dose-responsive manner and appears to protect the cells from oxidant-mediated cytolysis. |
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