ChemicalBook--->CAS DataBase List--->9013-72-3

9013-72-3

9013-72-3 Structure

9013-72-3 Structure
IdentificationBack Directory
[Name]

HEMOCYANIN, KEYHOLE LIMPET
[CAS]

9013-72-3
[Synonyms]

KLH
HEMOCYANIN
haemocyanin
HeMocyanins
blue carrier
HEMOCYANIN-HG
Keyhole limpet
BLUE CARRIER(R)
HEMOCYANIN TYPE VIII
KLH, BES/Mg2+ Buffer
hemocyanin from mollusk
KEYHOLE LIMPET HEMOCYANIN
HAEMOCYANIN KEYHOLE LIMPET
HEMOCYANIN, KEYHOLE LIMPET
HEMOCYANIN FROM CONCHOLEPAS
Hemocyaninfromkeyholelimpet
HEMOCYANIN FROM HORSESHOE CRAB
KLH (keyhole limpet hemocyanin)
hemocyanin from keyhole limpets
hemocyanin from megathura crenulata
HEMOCYANIN FROM KEYHOLE LIMPET 99+%
hemocyanin type viii lyophilized powder
hemocyanin from limulus polyphemus hemolymph
MALEIMIDE ACTIVATED KEYHOLE LIMPET HEMOCYANIN
HEMOCYANIN, KEYHOLE LIMPET, MEGATHURA CRENULATA
Hemocyanin solution from Megathura crenulata
Keyhole limpet hemocyanin, Protein ≥85 % by biuret
HEMOCYANIN FROM CONCHOLEPAS,STERILE PBS FORMULATION
HEMOCYANIN FROM KEYHOLE LIMPETS*(MEGATHU RA CRENULAT
hemocyanin from megathura crenulata (keyhole limpet)
HEMOCYANIN FROM KEYHOLE LIMPETS (MEGATHU RA CRENULATA)
HEMOCYANIN, KEYHOLE LIMPET, MEGATHURA CRENULATA, GLYCEROL
Hemocyanin, Keyhole Limpet, Megathura crenulata, BES/Mg2+ Buffer
HEMOCYANIN, KEYHOLE LIMPET, MEGATHURA CRENULATA, AMMONIUM SULFATE
Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin-Free, Glycerol
Hemocyanin, Keyhole Limpet, Megathura crenulata, High Purity, Endotoxin-Free, Sterile-Liquid
[MDL Number]

MFCD00131280
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

H2O: soluble
[form ]

PBS solution
[color ]

Off-white to gray
Safety DataBack Directory
[Risk Statements ]

52/53
[Safety Statements ]

23-24/25-61
[WGK Germany ]

1
[F ]

10-21
Hazard InformationBack Directory
[Uses]

Hemocyanin from Limulus polyphemus hemolymph has been used:
  • in electrophoretic field gradient focusing as a reference standard for optimizing fluorescence quenching for noncolored proteins
  • as standard protein for pH based crystallization screening experiments
  • in peptide conjugation studies

[Uses]

Keyhole limpet hemocyanin (KLH) is a strong and well known immune-stimulant in both experimental animals and humans. It has been used as a hapten carrier protein to enhance antigen-specific T cell priming and is known to stimulate a CD4+ T-cell response.
Hemocyanin was used to study if antipeptide antibodies specifically recognize the l1 protein of the human papilloma virus of type 31. It was also used to study the acid-induced unfolding of didecameric keyhole limpet hemocyanin.
[General Description]

Gastropod hemocyanins are massive glycoproteins (4 to 8 MDa) designed by an intricate arrangement of 10 subunits that are self-assembled into hollow cylinders 35 nm in diameter.
[Biochem/physiol Actions]

The largest hemocyanin molecules consisting of 48 (8 × 6) subunits are present in horseshoe crabs (Limulus polyphemus) have up to eight distinct subunits type (6 × subunit type I, 8 × II, 2 × IIA, 8 × IIIA, 8 × IIIB, 8 × IV, 4 × V, 4 × VI).
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