| Identification | Back Directory | [Name]
AMINOPEPTIDASE M | [CAS]
9054-63-1 | [Synonyms]
LAP
AP-M
CRP2
TCF5
TGF-β1
IL6DBP
hTGF-β1
anjitaimei
M/AP-M/LAP
EC 3.4.11.1
EC 3.4.11.2
AMINOPEPTIDASE M
Aminopeptidase PepN
Aminopeptidase M II
TGF-β1 Latent human
EC 3.4.11.2 TYPE VI
Leucinaminopeptidase
Alanyl aminopeptidase
Aminopeptidase N/CD13
EC 3.4.11.2 TYPE VI-S
EC 3.4.11.2 TYPE IV-S
cytoso[aminopeptidase
LEUCINE AMINOPEPTIDASE
Alanine aminopeptidase
AMINO ACID ARYLAMIDASE
AMINOPEPTIDASE M TYPE VI
Microsomal aminopeptidase
latency-associated peptide
AMINOPEPTIDASE M TYPE VI-S
AMINOPEPTIDASE M, 20 UNITS
AMINOPEPTIDASE M TYPE IV-S
AMINOPEPTIDASE M USP/EP/BP
LeucineAminopeptidase(LAP)
AMINOPEPTIDASE (MICROSOMAL)
membrane alanyl aminopeptidase
Native Porcine Aminopeptidase M
Arylamidase from Human placenta
Alanine-specific aminopeptidase
AMINOPEPTIDASE M, PORCINE KIDNEY
ALPHA-AMINOACYL-PEPTIDE HYDROLASE
Alanine aminopeptidase, microsomal
LEUCINE AMINOPEPTIDASE, MICROSOMAL
PARTICLE-BOUND AMINOPEPTIDASE TYPE VI
PARTICLE-BOUND AMINOPEPTIDASE TYPE VI-S
PARTICLE-BOUND AMINOPEPTIDASE TYPE IV-S
Transforming Growth Factor-β1 human
LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE VI
α-aminoacyl-peptide hydrolase (microsomal)
ALPHA-AMINOACYL-PEPTIDE HYDROLASE (CYTOSOL)
LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE VI-S
LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE IV-S
ALPHA-AMINOACYL-PEPTIDE HYDROLASE (MICROSOMAL)
Monoclonal Anti-CEBPB antibody produced in mouse
Native Porcine Leucine Aminopeptidase, microsomal
LEUCINE AMINOPEPTIDASE MICROSOMAL*SEQUEN CING GRADE
ALANINE AMINOPEPTIDASE FROM BOVINEINTEST INAL MUCOS
LEUCINE AMINOPEPTIDASE, MICROSOMAL TYPE IV-S FROM P
LEUCINE AMINOPEPTIDASE MICROSOMAL*TYPE V I FROM PORC
LEUCINE AMINOPEPTIDASE MICROSOMAL*TYPE V I-S FROM PO
leucine aminopeptidase, microsomal from porcine kidney
ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE VI
Transforming Growth Factor-β1 from human platelets
LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~5 U/MG*
LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~18 U/MG*
LEUCINE AMINOPEPTID., MICROS. FROM HOG KIDNEY, ~10 U/MG*
ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE VI-S
ALPHA-AMINOACYL-PEPTIDE HYDROLASE [MICROSOMAL] TYPE IV-S
Transforming Growth Factor-β1 from porcine platelets
Transforming Growth Factor-β1 Latency Associated Peptide human
Leucineaminopeptidasefromporcinekidneymicrosomesfreeze-driedpowder
α-Aminoacyl-Peptide Hydrolase (microsomal), Amino Acid Arylamidase, Aminopeptidase M, AP-M
Leucine Aminopeptidase, microsomal from porcine kidney Type IV-S, ammonium sulfate suspension, 10-40 units/mg protein (Bradford) | [EINECS(EC#)]
232-942-5 | [Molecular Formula]
C12H24O2 | [MDL Number]
MFCD00131501 |
| Hazard Information | Back Directory | [Uses]
Leucine Aminopeptidase, microsomal from porcine kidney has been used in aminopeptidase N (APN) inhibitor screening assay in adenocarcinoma cell line ES-2 and in the inhibition kinetic studies with APN inhibitor. | [Uses]
Transforming Growth Factor-β1 (TGF-β) human has been used :
- to study the expression of PDGFRB (Platelet derived growth factor receptor β) in association with transforming growth factor-β signaling.
- to stimulate lung fibrosis in human fetal lung fibroblast cell line in order to further measure the in-plane elasticity of live cell layers using a pressure sensor embedded microfluidic device.
- to study the effect of TGF-β on HTRA1 (high-temperature requirement A1)-affected Wnt target genes.
| [General Description]
The biologically active form of TGF-β1 (transforming growth factor-β1 human) exists as a disulphide-linked homodimer. In mammals, three isoforms of TGF-β has been identified : TGF-β1, TGF-β2 and TGF-β3. TGF-β1 encodes a 25 kDa peptide. TGF-β1 precursor polypeptide is characterized with hydrophobic signal sequence, pro-region and mature peptide. Cleavage of the precursor at tetrabasic cleavage site results in monomers of carboxy-terminal 112 amino acids. The TGF-β1 gene is mapped to human chromosome 19q13.2. | [Biochem/physiol Actions]
TGF-β1 is produced by many cell types, but is reported to be most concentrated in mammalian platelets, where it is present at approximately four times the level of TGF-β2. |
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Sigma-Aldrich
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021-61415566 800-8193336 |
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https://www.sigmaaldrich.cn |
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