| Identification | Back Directory | [Name]
Adrenalone | [CAS]
99-45-6 | [Synonyms]
u2134
adrenon
stypnon
remestyp
ketogaze
adrenone
chemosan
haemodan
kephrine
stryphnon
styphnone
stryphnone
ADRENALONE
NSC 243611
AKOS NCG-0050
Adrenalone USP/EP/BP
methaminoacetocatechol
Dipivefrine EP Impurity B
4-methylaminoacetocatechol
4-methylaminoacetopyrocatechol
3,4-DIHYDROXY-A-METHYLAMINOACETOPHENONE
3,4-dihydroxy-alpha-methylaminoacetophenone
3’,4’-dihydroxy-2-(methylamino)-acetophenon
3’,4’-dihydroxy-2-(methylamino)acetophenone
1-(3,4-dihydroxyphenyl)-2-(methylamino)-ethanon
1-(3,4-DIHYDROXY-PHENYL)-2-METHYLAMINO-ETHANONE
Ethanone, 1-(3,4-dihydroxyphenyl)-2-(methylamino)- | [EINECS(EC#)]
202-756-9 | [Molecular Formula]
C9H11NO3 | [MDL Number]
MFCD00707523 | [MOL File]
99-45-6.mol | [Molecular Weight]
181.19 |
| Chemical Properties | Back Directory | [Melting point ]
235.5°C (rough estimate) | [Boiling point ]
314.29°C (rough estimate) | [density ]
1.2375 (rough estimate) | [refractive index ]
1.5270 (estimate) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Aqueous Acid (Slightly) | [form ]
Solid | [pka]
7.32±0.20(Predicted) | [color ]
Pale Yellow to Light Yellow | [Stability:]
Hygroscopic |
| Hazard Information | Back Directory | [Originator]
Adrenalone ,Yick-Vic Chemicals and
Pharmaceuticals (HK) Ltd. | [Uses]
Adrenergic (ophthalmic). | [Definition]
ChEBI: Adrenalone is an aromatic ketone. | [Preparation]
Preparation by reaction of excess 33% aqueous methylamine with 3,4-dihydroxy-a-chloroacetophenone. | [Manufacturing Process]
To a suspension of 1 part ω-chloro-3,4-dihydroxyacetophenone (prerared from
chloroacetyl chloride and benzcatechole, see J. Russ. Phys. Chem. Ges., 25,
154) was added dropwise 1 part 60% solution of methylamine. Immediately
was formed a residue of the salt of methylamine and ω-chloro-3,4-
dihydroxyacetophenone. The dissolution of the salt was carried out by heating
of the mixture. Then the salt was converted in crude 3,4-dihydroxy-α-
methylaminoacetophenone. The product was dissolved in dilute hydrochloric
acid. To this solution was added dropwise aqueous ammonium solution to
prepare light yellow crystal of 3,4-dihydroxy-α-methylaminoacetophenone.
The base and the hydrochloride of 3,4-dihydroxy-α-methylaminoacetophenone
decomposed at temperature near 230°C and 240°C respectively. | [Therapeutic Function]
Hemostatic, Sympathomimetic, Vasoconstrictor |
|
| Company Name: |
Molsyns Research
|
| Tel: |
+91-9586858886 +91-9586858886 |
| Website: |
www.molsyns.com |
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