1445-07-4
中文名称
假尿苷
英文名称
BETA-PSEUDOURIDINE
CAS
1445-07-4
分子式
C9H12N2O6
分子量
244.2
MOL 文件
1445-07-4.mol
更新日期
2024/12/17 09:22:19
1445-07-4 结构式
基本信息
中文别名
假尿苷Β-假尿苷
5-Β-D-核呋喃基尿嘧啶
Β-PSEUDOURIDINE
PSEUDOURIDINE 假尿苷
英文别名
y-UridineNSC 162405
PSEUDOURIDINE
Pseudourindine
5-Ribosyluracil
Pseudouridine C
B-Pseudouridine
β-Pseudouridine
β-D-Pseudouridine
BETA-PSEUDOURIDINE
所属类别
生物化工：核苷类药物物理化学性质
熔点222 °C
密度1.641±0.06 g/cm3(Predicted)
储存条件Inert atmosphere,Room Temperature
溶解度甲醇（微溶，加热），水（微溶，超声处理，加热）
酸度系数(pKa)8.52±0.10(Predicted)
形态固体
颜色白色至灰白色
最大波长(λmax)264nm(MeOH)(lit.)
InChIInChI=1/C9H12N2O6/c12-2-4-5(13)6(14)7(17-4)3-1-10-9(16)11-8(3)15/h1,4-7,12-14H,2H2,(H2,10,11,15,16)/t4-,5-,6-,7+/s3
InChIKeyPTJWIQPHWPFNBW-IZFRNLNUNA-N
SMILESO[C@@H]1[C@@H]([C@@H](CO)O[C@H]1C1=CNC(=O)NC1=O)O |&1:1,2,3,7,r|
应用领域
用途1
An isomer of the nucleoside uridine found in all species and in many classes of RNA except mRNA. It is formed by enzymes called 唯 synthases, which post-transcriptionally isomerize specific uridine res
idues in RNA in a process termed pseudouridylation. Studies suggest that β-Pseudouridine reduces radiation-induced chromosome aberrations in human lymphocytes.