182563-08-2
182563-08-2 结构式
基本信息
LY 334370
Y 334370 HCL
LY 334370 HCL
LY 334370 HYDROCHLORIDE
LY334370
LY-334370
LY 334370
LY-334370 hydrochloride hydrate
4-Fluoro-N-(3-(1-methylpiperidin-4-yl)-1H-indol-5-yl)benazmide
4-Fluoro-N-[3-(1-methyl-piperidin-4-yl)-1H-indol-5-yl]-benzamide
BenzaMide, 4-fluoro-N-[3-(1-Methyl-4-piperidinyl)-1H-indol-5-yl]-
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | HY-103107 | 4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐 LY334370 | 182563-08-2 | 5mg | 800元 |
| 2024/04/30 | HY-103107 | 4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐 LY334370 | 182563-08-2 | 10mM * 1mLin DMSO | 880元 |
| 2024/04/30 | HY-103107 | 4-氟-N-(3-(1-甲基哌啶-4-基)-1H-吲哚-5-基)苯甲酰胺盐酸盐 LY334370 | 182563-08-2 | 10mg | 1200元 |
常见问题列表
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5-HT 1F Receptor 1.6 nM (Ki) |
LY334370 has no vasoconstrictor effects on human cerebral arteries in vitro until a dose of 10 -5 M, at which it produces a contraction of 8.5±5.7%; however, this is not significant.
Following intravenous administration of LY334370 at 3 mg/kg (n=3) or 10 mg/kg (n=6) electrical stimulation evokes an increase in dural blood vessel diameter of 135±6% and 106±11%, respectively, which is not significantly different from the respective control values. LY334370 has no effect on dural blood vessel diameter per se , since the actual dural blood vessel diameter is 43±4 arbitrary units before drug and 43±4 arbitrary units 15 min after injection of LY334370 (10 mg/kg).