21343-40-8
中文名称
25-羟麦角甾醇
英文名称
25-HYDROXYVITAMIN D2
CAS
21343-40-8
分子式
C28H44O2
MDL 编号
MFCD02683431
分子量
412.65
MOL 文件
21343-40-8.mol
更新日期
2024/09/10 09:45:57
![21343-40-8 结构式](/CAS/GIF/21343-40-8.gif)
基本信息
中文别名
25-羟麦角甾醇25-羟基维生素 D2
英文别名
25-hydroxyvitamind25-hydroxycalciferol
(E,3S,6S)-6-[(1R,3aR,4E,7aS)-4-[(2Z)-2-[(5S)-5-hydroxy-2-methylidene-cyclohexylidene]ethylidene]-7a-methyl-2,3,3a,5,6,7-hexahydro-1H-inden-1-yl]-2,3-dimethyl-hept-4-en-2-ol
25-hydoxyergocalciferol
3-{2-[1-(5-Hydroxy-1,4,5-trimethyl-hex-2-enyl)-7a-methyl-octahydro-inden-4-ylidene]-ethylidene}-4-methylene-cyclohexanol ( 25-Hydroxyvitamin D2 )
25-Hydroxycalciferol, 25-Hydroxyergocalciferol
(5Z,7E,22E)-25-Hydroxy-9,10-secoergosta-5,7,10(19),22-tetren-3β-ol
(5Z,7E,22E)-9,10-Secoergosta-5,7,10(19),22-tetrene-3β,25-diol
Ercalcidiol
所属类别
分析化学:标准物质物理化学性质
熔点45-51°C
沸点542.3±38.0 °C(Predicted)
密度1.02±0.1 g/cm3(Predicted)
闪点14℃
储存条件−20°C
溶解度Limited solubility, soluble in DMSO or ethanol
酸度系数(pKa)14.74±0.20(Predicted)
形态白色结晶性粉末。
颜色White to off-white
BRN4716773
稳定性对光敏感、对温度敏感
安全数据
警示词危险
危险性描述H225-H319
危险品标志T+,F
危险类别码24/25-26-48/25-11
安全说明28-36/37-45-16-7
危险品运输编号UN2811 6.1/PG 2
WGK Germany3
常见问题列表
生物活性
Ercalcidiol 是一种 vitamin D2 代谢物,作为 vitamin D 营养状态的指标。靶点
Human Endogenous Metabolite
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体外研究
Differentiation between Ercalcidiol (25(OH)D 2 ) and 25(OH)D 3 is important for monitoring vitamin D therapy, as vitamin D 2 is the predominant prescription form. The half-life of Ercalcidiol is shorter than that of 25(OH)D 3 and it binds less well to the vitamin D binding protein, making it less potent and, therefore, required to be administered at much higher doses than vitamin D 3 . Some currently used assays have a diminished capacity to detect Ercalcidiol, which can lead to dangerous overdosing when attempting to monitor therapy with vitamin D 2 .