62992-61-4
![62992-61-4 结构式](/CAS/GIF/62992-61-4.gif)
基本信息
中文别名
依特柳酯 英文别名
Daitaleterilate
Eterylate
etersalate
Etherylate
2-[4-(Acetylamino)phenoxy]ethyl 2-(acetoxy)benzoate
2-Acetyloxybenzoic acid 2-[4-(acetylamino)phenoxy]ethyl ester
Benzoic acid, 2-(acetyloxy)-, 2-[4-(acetylamino)phenoxy]ethyl ester
物理化学性质
熔点139-141°
沸点561.8±40.0 °C(Predicted)
密度1.263±0.06 g/cm3(Predicted)
储存条件-20°C储存
溶解度溶于二甲基亚砜
酸度系数(pKa)14.49±0.70(Predicted)
常见问题列表
生物活性
Eartsalate 抑制血小板功能并降低血栓素 A2 (TXA2) 水平。靶点
TXA 2
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体外研究
Ex vivo antiplatelet properties of Etersalate and its effects on serum thromboxane A2 (TXA2) levels and prostaglandin I2 (PGI2) generation are studied in human volunteers at two levels of oral dosing. Etersalate inhibits at the lower dosage platelet function and decreased TXA2 levels, but PGI2 generation from rat aortic rings is stimulated when incubated with plasma from Etersalate-treated donors. Blood coagulation parameters remain within normal values. Etersalate administration can act on platelet arachidonate metabolism at a different level than that of the cyclooxygenase pathway.