64490-92-2
![64490-92-2 结构式](/CAS/GIF/64490-92-2.gif)
基本信息
托尔米汀钠
托美丁钠(二水)
2-[1-甲基-5-(4-甲基苯甲酰)吡咯-2-基]乙酸钠(二水)
1-METHYL-5-[P-TOLUOYL]PYRROLE-2-ACETIC ACID SODIUM SALT: DIHYDRATE
TOLMETIN SODIUM
TOLMETIN SODIUM SALT DIHYDRATE
TOLMETIN SODIUM SALT: DIHYDRATE
1h-pyrrole-2-aceticacid,1-methyl-5-(4-methylbenzoyl)-,sodiumsalt,dihydrate
sodium1-methyl-5-p-toluoylpyrrole-2-acetatedihydrate
sodiumtolmetindihydrate
tolmetinsodiumdihydrate
Tolmetinsodiumsaltdihydratecrystalline
1-methyl-5-(p-toluoyl)pyrrole-2-acetic acid sodium-potassium salt dihydrate
TOLMELINSODIUM
1-Methyl-5-(4-methylbenzoyl)-1H-pyrrole-2-acetic Acid Sodium Dihydrate
1-Methyl-5-p-toluoylpyrrole-2-acetic Acid Sodium Dihydrate
5-[(p-Tolyl)carbonyl]-1-methylpyrrole-2-acetic Acid Sodium Dihydrate
McN 2559-21-98
Tolmene
1-Methyl-5-(p-toluoyl)pyrrole-2-acetic acid dihydrate sodium-potassium salt
Tolmetin dihydrate sodium salt
报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
2024/08/19 | HY-B1489 | 托美丁钠(二水) Tolmetin sodium dihydrate | 64490-92-2 | 100mg | 500元 |
2024/08/19 | HY-B1489 | 托美丁钠(二水) Tolmetin sodium dihydrate | 64490-92-2 | 10mM * 1mLin DMSO | 550元 |
2024/08/19 | S4360 | 托美丁钠(二水) Tolmetin Sodium | 64490-92-2 | 25mg | 795.3元 |
常见问题列表
Human COX-1 0.35 μM (IC 50 ) |
Human COX-2 0.82 μM (IC 50 ) |
Tolmetin sodium dihydrate (0.25 mM) does not attenuate lipid peroxidation in rat brain homogenate. Tolmetin (0.25, 0.5, 0.75, 1 mM) shows radical scavenging properties but without superoxide anion generation in rat brain homogenat.
Tolmetin sodium dihydrate (0.001-100 μM) shows anticancer activity againts HT-29 colon cancer cell line in a dose-dependent manner.
Tolmetin sodium dihydrate (0-100 μM) shows no effect on osteoblast growth.
Tolmetin sodium dihydrate (30,100 mg/kg; gavage; single dose or twice daily for 3 and 14 days) shows maximal ulcerogenic effect 4 h after the single dose, while potently decreases after 3 and 14 days of repeated administration in male Wistar rats weighing 180-200 g. Tolmetin causes gastric lesions in 100 mg/kg.
Tolmetin sodium dihydrate (5 mg/kg twice a day for 5 days) pre-treatment considerably attenuates quinolinic acid (QA)-induced neurotoxicity.