69-93-2
![69-93-2 结构式](/CAS/GIF/69-93-2.gif)
基本信息
尿酸
2,6,8-三羟基嘌呤
尿酸,标准液
尿酸,参比液
2,6,8,-三羟基尿杂环
2,6,8,-三羟基嘌呤
三氧化嘌呤
2,6,8-嘌呤三酮
2,6,8-三羥嘌呤
2,6,8-TRIOXYPURINE
8-HYDROXYXANTHINE
LABOTEST-BB LT00233143
LITHIC ACID
PURINE-2,6,8(1H,3H,9H)-TRIONE
PURINE-2,6,8-TRIOL
TRIKETOPURINE
URIC ACID
URIC OXIDE
1H-Purine-2,6,8(3H)-trione, 7,9-dihydro-
1H-Purine-2,6,8(3H)-trione,7,9-dihydro-
1H-Purine-2,6,8-triol
2,6,8-Trioxopurine
6,8(3H)-trione,7,9-dihydro-1H-Purine-2
7,9-Dihydro-1H-purine-2,6,8(3H)-trione
8(3h)-trione,7,9-dihydro-1h-purine-6
Purine-3,6,8(1H,3H,9H)-trione
Urease tablets from jack beans
URIC ACID, 99+%
物理化学性质
安全数据
制备方法
1.取干燥鸡粪悬浮于24倍量水中,加入适量氢氧化钙后静置。沉淀完全后分出上清液,沉淀中再加水,用硝酸调节pH值至3,静置至沉淀完全。分出上清液,沉淀物再悬浮在水中,以氢氧化钙调节pH值至12~12.5,过滤后滤液以硝酸调pH值至3,析出物过滤、干燥后即为尿酸粗品。
常见问题列表
Human Endogenous Metabolite
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Uric acid is an endogenous antioxidant that scavenges reactive oxygen species (ROS) including singlet oxygen, oxygen radicals, and peroxynitrite. Incubation with indomethacin significantly increases malondialdehyde (MDA) levels in Caco-2 cells compare to those not treated indomethacin. Incubation with both indomethacin and Uric acid significantly decreases MDA levels compare to those grown in the presence of indomethacin alone. Co-treatment of cells with indomethacin and Uric acid significantly decreases ROS levels compare to those in cells incubated with indomethacin alone. Cell viability in Caco-2 cells treated with both indomethacin and Uric acid is higher than that in cells treated with indomethacin alone. Uric acid has a protective effect on indomethacin-induced intestinal cell changes through its antioxidant activity.
When mice treated with indomethacin are concurrently administered Uric acid orally, ulcer areas are significantly reduced, in a Uric acid dose-dependent manner. Indomethacin increases the ratio of crypt depth to villous height in the ileum, while the ratio is significantly lower when mice are concurrently administered Uric acid orally. Administration of indomethacin also increases the histopathological score of tissue damage in the small intestine, while mice concurrently administered Uric acid orally has a significantly lower histopathological score. The ileal levels of malondialdehyde (MDA) in indomethacin-induced enteropathy model mice orally administered Uric acid are also significantly lower than the levels in mice administered indomethacin alone.
知名试剂公司产品信息
Uric acid, 99+%(69-93-2)
Uric acid, 99%(69-93-2)
Uric Acid,>98.0%(T)(69-93-2)