75541-83-2
中文名称
EXO 1
英文名称
EXO1
CAS
75541-83-2
分子式
C15H12FNO3
分子量
273.26
MOL 文件
75541-83-2.mol
更新日期
2024/06/22 07:11:28
75541-83-2 结构式
基本信息
中文别名
化合物EXO12- [(4-氟苯甲酰基)氨基]苯甲酸甲酯
英文别名
EXO1EOX 1
NSC 214045
EXOCYTIC INHIBITOR 1
4-FLUORO-BZ-2-ABZ-OME
2-(4-Fluoro-benzoylami
Exo 1 >=98% (HPLC), solid
Exo1 - CAS 75541-83-2 - Calbiochem
2-(4-FLUOROBENZOYLAMINO)METHYLBENZOATE
EXOCYTIC INHIBITOR 1
NSC 214045
EXO 1
EXO-1
EXO 1价格(试剂级)
| 报价日期 | 产品编号 | 产品名称 | CAS号 | 包装 | 价格 |
| 2024/04/30 | S6800 | EXO 1 Exo1 | 75541-83-2 | 5mg | 390.25元 |
| 2023/03/20 | S6800 | EXO 1 Exo1 | 75541-83-2 | 25mg | 1265.48元 |
常见问题列表
生物活性
Exo1 (2-(4-Fluorobenzoylamino)-benzoic acid methyl ester)是一种针对 exocytosis 的可逆抑制剂，可诱导 Golgi 迅速塌陷至内质网和来自高尔基体的 ADP-ribosylation factor (ARF) 1 的快速释放。靶点
| Target | Value |
|
exocytosis
() | |
|
Golgi
() | |
|
ARF-1
() |
体外研究
Exo1 is a modifier of Golgi ARF1 GTPase activity. Because Exo1 affects a subset of the membrane events that are blocked by BFA, but seems to have a different protein target (and presumably has different side effects), it provides an independent means to interfere with Golgi activity. Exo1 Disrupts Vesicular Traffic from the ER to the Golgi apparatus by disrupting Golgi structures. Exo1 inhibits exocytosis with an IC 50 of ~20 μM. Exo1 prevents acquisition of endoglycosidase H resistance by newly synthesized proteins such as VSVGts-GFP, transferrin, and MHC class I.