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853-23-6

中文名称 醋酸去氢表雄酮
英文名称 Dehydroepiandrosterone acetate
CAS 853-23-6
分子式 C21H30O3
分子量 330.46
MOL 文件 853-23-6.mol
更新日期 2024/11/13 10:07:05
853-23-6 结构式 853-23-6 结构式

基本信息

中文别名
重排
醋酸脱氢异雄酮
醋酸去氢表雄酮
醋酸去氢素雄酮
乙酸脱氢异雄甾酮
去氢表雄酮醋酸酯
3-醋酸去氢表雄酮
3-乙酸脱氢异雄甾酮
乙酸反式脱氢异雄素酮
醋酸去氢表雄酮(甾体)
英文别名
skf2847
PRASTERONE ACETATE
androstenoloneacetate
3B-ACETOXY-5-ANDROSTEN-17-ONE
dehydroandrosterone 3-acetate
3β-Acetoxyandrost-5-en-17-one
DEHYDROISOANDROSTERONE ACETATE
DEHYDROISOANDROSTERONE ACATATE
3-β-acetoxy-5-androsten-17-one
Dehydroepiandrosterone acetate
所属类别
分析化学:分析标准品

物理化学性质

熔点168-170 °C(lit.)
沸点407.89°C (rough estimate)
密度1.0998 (rough estimate)
蒸气压0Pa at 20℃
折射率1.5192 (estimate)
储存条件Refrigerator
溶解度可溶于氯仿、DMSO(微溶)、甲醇(微溶)
形态固体
颜色白色至灰白色
旋光性 (optical activity)[α]20/D +2.4°, c = 2 in ethanol
水溶解性11.5mg/L(temperature not stated)
InChIInChI=1/C21H30O3/c1-13(22)24-15-8-10-20(2)14(12-15)4-5-16-17-6-7-19(23)21(17,3)11-9-18(16)20/h4,15-18H,5-12H2,1-3H3/t15-,16-,17-,18-,20-,21-/s3
InChIKeyNCMZQTLCXHGLOK-KJBVPOJVSA-N
SMILESC[C@]12CC[C@H](OC(=O)C)CC1=CC[C@@]1([H])[C@]3([H])CCC(=O)[C@@]3(C)CC[C@]21[H] |&1:1,4,13,15,21,25,r|
LogP5.1 at 20℃
CAS 数据库853-23-6

安全数据

危险性符号(GHS)GHS hazard pictograms
GHS08
警示词危险
危险性描述H360
安全说明22-24/25
WGK Germany3
RTECS号BV8396810

应用领域

用途1
用于合成甾体激素药物
用途2
醋酸去氢表雄酮是合成各种激素、计划生育用品等甾体激素类药物的重要中间体,由它可合成睾丸素、甲基睾丸素、雌二醇、雌三醇

上下游产品信息

醋酸去氢表雄酮价格(试剂级)
报价日期产品编号产品名称CAS号包装价格
2024/11/11XW08532363醋酸去氢表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-6100G659元
2024/11/11XW08532362醋酸去氢表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-625G194元
2024/11/11XW08532361醋酸去氢表雄酮
dehydroisoandrosterone 3-acetate;3β-acetoxy-5-androsten-17-one;3β-hydroxyandrost-5-en-17-one acetate;dehydroepiandrosterone 3-acetate;presterone acetate
853-23-65G54元

常见问题列表

生物活性
Dehydroepiandrosterone 3-acetate 是雄性激素/雌性激素的前体物质,能够调节脊椎动物的攻击性行为。
体内研究

Dehydroisoandrosterone implants increases aggression in a laboratory-based simulated territorial intrusion. Brains of Dehydroisoandrosterone-implanted birds show higher aromatase mRNA expression in the preoptic area (POA) and higher androgen receptor mRNA expression in the periventricular nucleus of the medial striatum (pvMSt) and ventromedial nucleus of the hypothalamus (VMH). The Dehydroisoandrosterone-induced increases in aromatase expression in the POA and androgen receptor expression in the pvMSt are consistent with previously reported seasonal increases in these markers associated with naturally elevated Dehydroisoandrosterone levels. Dehydroisoandrosterone supplementation (10.2 mg/kg) alone significantly increases mice body weight (BW), muscle weight, testosterone level, and glycogen contents (liver and muscle) when compared with SC group.

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