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95232-68-1

中文名称 替诺柳
英文名称 Tenosal
CAS 95232-68-1
分子式 C12H8O4S
分子量 248.25
MOL 文件 95232-68-1.mol
95232-68-1 结构式 95232-68-1 结构式

基本信息

中文别名
替诺柳
英文别名
Tenosal
2-(2-thiophenecarboxy)benzoic acid
2-(thiophene-2-carbonyloxy)benzoic acid
2-Thiophenecarboxylic acid, 2-carboxyphenyl ester

物理化学性质

储存条件-20°C储存
溶解度溶于二甲基亚砜

安全数据

危险性符号(GHS)
GHS07
警示词警告
危险性描述H302-H315-H319-H335

常见问题列表

生物活性
Tenosal 是一种通过将水杨酸与 2-噻吩羧酸酯化而得到的新型化合物,具有抗炎,镇痛和退热特性。
体内研究

Tenosal is a new compound obtained by esterifying salicylic acid with 2-thiophene-carboxylic acid and displays anti-inflammatory, analgesic and antipyretic properties. Extraction recovery measured is on average 95.75% for Tenosal, 98.71% for salicylic acid (SA) and 91.11% for TA. In the whole analysis of Tenosal extracted from plasma, the inter-assay coefficient of variation (C.V.) ranges from 1.00 to 5.86% and the intra assay C.V. is 5.01%. The administration of Tenosal allows a higher bioavailability of SA to be achieved than after dosing with ASA.

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