黄夹次甙乙
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- CAS号:
- 466-07-9
- 英文名:
- NERIIFOLIN
- 英文别名:
- NERIIFOLIN;17α-Neriifolin;17β-Neriifolin;xy)-14-hydroxy-;NERIIFOLIN USP/EP/BP;digitoxigenin+thevetose;14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside);3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide;3β-[(3-O-Methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide;3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14β-hydroxy-5β-carda-20(22)-enolide
- 中文名:
- 黄夹次甙乙
- 中文别名:
- 黄夹次甙乙;化合物 NERIIFOLIN
- CBNumber:
- CB0229805
- 分子式:
- C30H46O8
- 分子量:
- 534.68
- MOL File:
- 466-07-9.mol
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黄夹次甙乙化学性质
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熔点:
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218-225°C
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比旋光度:
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D23 -50.2° (CH3OH)
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储存条件:
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2-8°C
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溶解度:
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Chloroform(Slightly), DMSO(Slightly), Methanol (Slightly), Water (Slightly)
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形态:
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Solid
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颜色:
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Pale Yellow
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黄夹次甙乙性质、用途与生产工艺
Neriifolin 是一种穿透中枢神经系统的强心苷，是一种Na+, K+-ATPase 的抑制剂。Neriifolin 可靶向 beclin 1，抑制 LC3 相关吞噬体的形成，改善实验性自身免疫性脑脊髓炎 (EAE) 的发展。Neriifolin 诱导人肝癌 HepG2 细胞周期阻滞和凋亡。
Neriifolin (0.1μg/mL; 48 hours) induces apoptosis in HepG2 cells. Neriifolin (0-8 μg/mL; 72 hours) reduces viability of HepG2 cells. Neriifolin also induces S and G2/M phase arrests of the cell cycle and stimulates apoptosis of HepG2 cells. Stimulation of HepG2 cells with Neriifolin induced activation of caspase-3, -8, and -9, and up-regulated expression of Fas and FasL proteins.
黄夹次甙乙
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-N8441 | Neriifolin | | 1 mg | 2045元 |
| 2024/11/08 | HY-N8441 | 黄夹次甙乙
Neriifolin | 466-07-9 | 5mg | 4500元 |
466-07-9, 黄夹次甙乙 相关搜索:
- 抑制剂
- 中草药成分
- 化合物 NERIIFOLIN
- 黄夹次甙乙
- 466-07-9
- NERIIFOLIN USP/EP/BP
- 17β-Neriifolin
- Card-20(22)-enolide, 3-[(6-deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-, (3β,5β)-
- 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside)
- 3β-[(6-Deoxy-3-O-methyl-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
- 3β-[(3-O-Methyl-6-deoxy-α-L-glucopyranosyl)oxy]-14-hydroxy-5β-card-20(22)-enolide
- 3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14β-hydroxy-5β-carda-20(22)-enolide
- 17α-Neriifolin
- (17R)-3β-(3-O-Methyl-6-deoxy-α-L-glucopyranosyloxy)-14-hydroxy-5β,14β-carda-20(22)-enolide
- (5beta)-3beta-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- (3-beta,5-beta)-3-[(6-deoxy-3-O-methyl-alpha-L-glucopyranosyl)oxy]-14-hydroxycard-20(22)-enolide
- xy)-14-hydroxy-
- digitoxigenin+thevetose
- NERIIFOLIN
- 14-Hydroxy-5β-card-20(22)-enolide 3-(6-deoxy-3-O-methyl-α-L-glucopyranoside), 3-([6-Deoxy-3-O-methyl-α-L-glucopyranosyl]oxy)-14-hydroxy-5β-card-20(22)-enolide]