化合物TRPM4-IN-1
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- CAS号:
- 351424-20-9
- 英文名:
- 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid
- 英文别名:
- TRPM4-IN-1;TRPM4-IN-5;CBA (TRPM4-IN-5);TRPM4 inhibitor 5;4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid;4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid;Benzoic acid, 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]-;TRP Channel,Transient receptor potential channels,non-selective,TRPM4IN1,diseases,TRPM4,inhibit,Inhibitor,TRPM-4-IN-1,TRPM4 IN 1,cancer,cation,cardiac,channel,prostate,calcium-activated
- 中文名:
- 化合物TRPM4-IN-1
- 中文别名:
- CBA,TRPM4阻滞剂;化合物TRPM4-IN-1;4-氯-2-(2-(2-氯苯氧基)乙酰氨基)苯甲酸
- CBNumber:
- CB14112210
- 分子式:
- C15H11Cl2NO4
- 分子量:
- 340.16
- MOL File:
- 351424-20-9.mol
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化合物TRPM4-IN-1化学性质
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形态:
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A solid
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颜色:
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White to yellow
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化合物TRPM4-IN-1性质、用途与生产工艺
TRPM4-IN-1 (CBA) 是一种有效的、选择性的阳离子通道 TRPM4 抑制剂，其 IC50 为 1.5 μM。TRPM4-IN-1 可用于心脏病和前列腺癌的研究。
TRPM4-IN-1 (compound 5) is a potent and selective inhibitor of TRPM4 current in TRPM4 overexpressed HEK293 cells.
TRPM4-IN-1 reversibly blocks endogenous TRPM4 currents in LNCaP (prostate cancer) cells.
TRPM4-IN-1 (50 μM; Overnight) restores functional expression of A432T, a loss‐of‐expression TRPM4 variant.
Western Blot Analysis
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Cell Line:
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HEK293 cells
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Concentration:
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50 μM
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Incubation Time:
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Overnight
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Result:
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Partial rescued the total and surface expression of A432T.
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化合物TRPM4-IN-1
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-122605 | TRPM4-IN-1 | | 5 mg | 437元 |
| 2024/11/08 | HY-122605 | 化合物TRPM4-IN-1
TRPM4-IN-1 | 351424-20-9 | 10mg | 700元 |
351424-20-9, 化合物TRPM4-IN-1 相关搜索:
- 抑制剂
- 合成有机化合物配体
- CBA,TRPM4阻滞剂
- 4-氯-2-(2-(2-氯苯氧基)乙酰氨基)苯甲酸
- 化合物TRPM4-IN-1
- 351424-20-9
- TRP Channel,Transient receptor potential channels,non-selective,TRPM4IN1,diseases,TRPM4,inhibit,Inhibitor,TRPM-4-IN-1,TRPM4 IN 1,cancer,cation,cardiac,channel,prostate,calcium-activated
- CBA (TRPM4-IN-5)
- TRPM4 inhibitor 5
- TRPM4-IN-1
- TRPM4-IN-5
- Benzoic acid, 4-chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]-
- 4-Chloro-2-[[2-(2-chlorophenoxy)acetyl]amino]benzoic acid
- 4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid