ApovincaMinic Acid Hydrochloride Salt
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- CAS号:
- 72296-47-0
- 英文名:
- ApovincaMinic Acid Hydrochloride Salt
- 英文别名:
- Vinpocetine Carboxylic Acid HCl;ApovincaMinic Acid Hydrochloride Salt;Vinpocetine Carboxylic Acid HCl (Apovincaminic Acid HCl)
- 中文名:
- ApovincaMinic Acid Hydrochloride Salt
- 中文别名:
- CBNumber:
- CB22695631
- 分子式:
- C20H23ClN2O2
- 分子量:
- 358.87
- MOL File:
- 72296-47-0.mol
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ApovincaMinic Acid Hydrochloride Salt化学性质
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熔点:
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>236°C (dec.)
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储存条件:
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Hygroscopic, Refrigerator, under inert atmosphere
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溶解度:
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DMSO (Slightly), Methanol (Slightly), Water (Very Slightly)
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形态:
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Solid
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颜色:
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White
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稳定性:
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Hygroscopic
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ApovincaMinic Acid Hydrochloride Salt性质、用途与生产工艺
Apovincaminic acid hydrochloride salt 是 Vinpocetine (VP) 的一种具有口服活性和可透过血脑屏障的主要活性代谢产物。Apovincaminic acid hydrochloride salt 具有神经保护作用。
Apovincaminic acid (10 mg/kg; i.p. twice daily for 4 days) effectively attenuates the behavioral deficits, and significantly decreases lesion size and the region of microglia activation.
Apovincaminic acid (10 mg/kg; p.o.) is absorbed 50% of the dose comparing with i.v. administration in rats.
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Animal Model:
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Male Harlan‐Wistar rats (300-400 g) are injected NMDA
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Dosage:
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10 mg/kg
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Administration:
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I.p. twice daily for 4 days
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Result:
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Attenuated the attention deficit effectively.
Prevented the learning and memory impairment in the spontaneous alternation and Morris water maze tests.
significantly reduced lesion size microglia activation.
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ApovincaMinic Acid Hydrochloride Salt
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-133813A | Apovincaminic acid hydrochloride salt | | 1 mg | 500元 |
| 2024/04/30 | HY-133813A | ApovincaMinic Acid Hydrochloride Salt
Apovincaminic acid hydrochloride salt | 72296-47-0 | 5mg | 1100元 |
ApovincaMinic Acid Hydrochloride Salt
生产厂家
72296-47-0, ApovincaMinic Acid Hydrochloride Salt 相关搜索:
- Chiral Reagents, Heterocycles, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
- 抑制剂
- 72296-47-0
- Vinpocetine Carboxylic Acid HCl
- Vinpocetine Carboxylic Acid HCl (Apovincaminic Acid HCl)
- ApovincaMinic Acid Hydrochloride Salt