Prodipine (hydrochloride)
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- CAS号:
- 31314-39-3
- 英文名:
- Prodipine (hydrochloride)
- 英文别名:
- Prodipine (hydrochloride)
- 中文名:
- Prodipine (hydrochloride)
- 中文别名:
- 普罗地平盐酸盐;化合物 T13826
- CBNumber:
- CB23175574
- 分子式:
- C20H26ClN
- 分子量:
- 315.89
- MOL File:
- 31314-39-3.mol
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Prodipine (hydrochloride)化学性质
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熔点:
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267°
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形态:
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Solid
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颜色:
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Off-white to yellow
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Prodipine (hydrochloride)性质、用途与生产工艺
Prodipine 是一种二苯基膦酸酯衍生物。抑制兔纯化的和血浆中的二肽基肽酶 IV (DPP IV),IC50 分别为 4.5 μM 和 30 μM。
IC50: 4.5 μM (purified DPP IV), 30 μM (plasma DPP IV)
Prodipine, a diphenyl-phosphonate derivative selected from a group of slow-binding irreversible inhibitors of this enzyme. The IC
50
values of Prodipine for purified and plasma DPP IV from the rabbit are 4.5 μM and 30 μM, respectively.
Male rabbits weighing 3-4 kg receive a single intravenous injection with 10 mg Prodipine or saline. After 1 hr, plasma DPP IV activity has decreased to less than 20% of the preinjection value and remaines unchanged during a 24 hr observation period. A profound and long-lasting inhibition of plasma DPP IV activity is observed in the treated animals (1, 5 or 10 mg). It takes 5 to 8 days to reach half of the pretreatment DPP IV activity and generally more than 20 days for a complete recovery.
Prodipine (hydrochloride)
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-101605 | Prodipine (hydrochloride) Prodipine hydrochloride | 31314-39-3 | 1 mg | 1000元 |
2024/08/19 | HY-101605 | Prodipine hydrochloride | | 5 mg | 2500元 |
Prodipine (hydrochloride)
生产厂家
31314-39-3, Prodipine (hydrochloride) 相关搜索:
- 化合物 T13826
- 普罗地平盐酸盐
- 31314-39-3
- Prodipine (hydrochloride)