GEN6776
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- CAS号:
- 2009273-71-4
- 英文名:
- GEN6776
- 英文别名:
- GEN6776;CS-2823;GNE-6776;GEN6776 GNE-6776;GNE-6776, 10 mM in DMSO;GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776;6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide;6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide;[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-;5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
- 中文名:
- GEN6776
- 中文别名:
- 化合物GEN6776;PERFEMIKER]GEN6776,98%;化合物GEN6776,10 MM DMSO 溶液;6'-氨基-4'-乙基-5'- (4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺;6'-氨基-4'-乙基-5'- (4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺
- CBNumber:
- CB23367720
- 分子式:
- C20H20N4O2
- 分子量:
- 348.4
- MOL File:
- 2009273-71-4.mol
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GEN6776化学性质
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沸点:
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609.7±55.0 °C(Predicted)
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密度:
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1.242±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO : ≥ 310 mg/mL (889.78 mM)
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形态:
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Solid
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酸度系数(pKa):
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8.14±0.15(Predicted)
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颜色:
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White to off-white
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GEN6776性质、用途与生产工艺
GNE-6776 是一种有效的、非共价的、选择性和口服生物利用度的 USP7 的抑制剂，对于全长USP7和USP7催化域，对应的IC50值分别为1.34 μM 和 0.61 μM。
| Target | Value |
USP7 catalytic domain
(Cell-free assay)
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0.61 μM
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full length USP7
(Cell-free assay)
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1.34 μM
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GEN6776
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2025/02/08 | HY-107986 | GNE-6776 | 2009273-71-4 | 1 mg | 1000元 |
| 2025/02/08 | HY-107986 | GEN6776
GNE-6776 | 2009273-71-4 | 5mg | 2200元 |
2009273-71-4, GEN6776 相关搜索:
- API
- 抑制剂
- 化工试剂
- 中药对照品
- 化合物GEN6776,10 MM DMSO 溶液
- PERFEMIKER]GEN6776,98%
- 6'-氨基-4'-乙基-5'- (4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺
- 化合物GEN6776
- 6'-氨基-4'-乙基-5'- (4-羟基苯基)-N-甲基-[3,3'-联吡啶]-6-甲酰胺
- 2009273-71-4
- GNE-6776, 10 mM in DMSO
- 6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
- GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776
- 5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
- [3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-
- 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
- GEN6776 GNE-6776
- CS-2823
- GNE-6776
- GEN6776