ChemicalBook >> CAS DataBase List >>GEN6776
GEN6776
- CAS No.
- 2009273-71-4
- Chemical Name:
- GEN6776
- Synonyms
- GEN6776;CS-2823;GNE-6776;GEN6776 GNE-6776;GNE-6776, 10 mM in DMSO;GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776;6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide;[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-;5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
- CBNumber:
- CB23367720
- Molecular Formula:
- C20H20N4O2
- Molecular Weight:
- 348.4
- MDL Number:
- MFCD31657364
- MOL File:
- 2009273-71-4.mol
Last updated:2025-04-17 18:22:24
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
GEN6776 price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | BG166813 | GNE 6776 | 2009273-71-4 | 10mg | $185 | 2021-12-16 | Buy |
| ChemScene | CS-0031103 | GNE-6776 98.29% | 2009273-71-4 | 5mg | $220 | 2021-12-16 | Buy |
| AK Scientific | 3226EH | 5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide | 2009273-71-4 | 10mg | $299 | 2021-12-16 | Buy |
| ChemScene | CS-0031103 | GNE-6776 98.29% | 2009273-71-4 | 10mg | $350 | 2021-12-16 | Buy |
| Biosynth Carbosynth | BG166813 | GNE 6776 | 2009273-71-4 | 50mg | $647.5 | 2021-12-16 | Buy |
GEN6776 Chemical Properties,Uses,Production
Uses
GNE6776, is a selective USP7 inhibitor.
in vivo
GNE-6776 (100 or 200 mg/kg; oral gavage on a once or twice daily schedule; for 10 days) inhibits EOL-1 xenograft growth in mice[1].
| Animal Model: | Immunodeficient C.B-17 SCID mice (aged 12-16 weeks) with EOL1 AML xenograft[1] |
| Dosage: | 100 or 200?mg/kg |
| Administration: | Oral gavage on a once or twice daily schedule; for 10 days |
| Result: | Significant EOL-1 xenograft growth inhibition. |
GEN6776 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 61)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 33024 | 60 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Chemia Biotechnology（Shanghai） Co., Ltd | +8613816753574 | info@chemia-pharm.com | CHINA | 311 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Qingdao Dexin Chemical Co., Ltd | +86-15553333686 +86-15553333686 | 15553333686@qq.com | China | 3113 | 58 |
GEN6776
GNE-6776
CS-2823
GEN6776 GNE-6776
6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide
[3,3'-Bipyridine]-6-carboxamide, 6'-amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-
5-[6-Amino-4-ethyl-5-(4-hydroxyphenyl)pyridin-3-yl]-N-methylpyridine-2-carboxamide
GNE6776,GNE-6776,Deubiquitinase,DUBs,Inhibitor,inhibit,GNE 6776
GNE-6776, 10 mM in DMSO
2009273-71-4
API