DBCO-PEG4-NH-Boc
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- CAS号:
- 1255942-12-1
- 英文名:
- DBCO-PEG4-NH-Boc
- 英文别名:
- DBCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-t-Boc Amine;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
- 中文名:
- DBCO-PEG4-NH-Boc
- 中文别名:
- DBCO-PEG4-氨基甲酸叔丁酯;二苯并环辛炔-NHCO-四聚乙二醇-NH-BOC;二苯并环辛炔-NHCO-四聚乙二醇-氨基-叔丁酯;二苯并环辛炔-NHCO-四聚乙二醇-NH-叔丁酯;化合物 DBCO-NHCO-PEG4-NH-BOC
- CBNumber:
- CB23373604
- 分子式:
- C34H45N3O8
- 分子量:
- 623.74
- MOL File:
- 1255942-12-1.mol
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DBCO-PEG4-NH-Boc化学性质
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沸点:
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840.5±65.0 °C(Predicted)
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密度:
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1.21±0.1 g/cm3(Predicted)
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溶解度:
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Soluble in DMSO, DCM, DMF
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形态:
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Viscous Liquid
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酸度系数(pKa):
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12.23±0.46(Predicted)
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颜色:
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Colorless to yellow
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DBCO-PEG4-NH-Boc性质、用途与生产工艺
DBCO-NHCO-PEG4-NH-Boc 是一种 PROTAC 连接桥，属于 PEG 类和 Alkyl/ether 类。DBCO-NHCO-PEG4-NH-Boc 可用于合成一系列 PROTAC 分子。DBCO-NHCO-PEG4-NH-Boc 是一种可降解 (cleavable) 的 ADC 连接桥，用于抗体药物结合物 (ADCs) 的合成。
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Cleavable
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PEGs
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Alkyl/ether
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PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
DBCO-PEG4-NH-Boc
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-126884 | DBCO-NHCO-PEG4-NH-Boc | | 25 mg | 435元 |
| 2024/11/08 | HY-126884 | DBCO-NHCO-PEG4-NH-Boc | | 50 mg | 697元 |
1255942-12-1, DBCO-PEG4-NH-Boc 相关搜索:
- 抑制剂
- C34H45N3O8
- 化合物 DBCO-NHCO-PEG4-NH-BOC
- 二苯并环辛炔-NHCO-四聚乙二醇-NH-BOC
- 二苯并环辛炔-NHCO-四聚乙二醇-氨基-叔丁酯
- 二苯并环辛炔-NHCO-四聚乙二醇-NH-叔丁酯
- DBCO-PEG4-氨基甲酸叔丁酯
- 1255942-12-1
- 5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
- DBCO-NHCO-PEG4-t-Boc Amine
- DBCO-NHCO-PEG4-NH-Boc
- DBCO-PEG4-NH-Boc