DBCO-PEG4-NH-Boc
- CAS No.
- 1255942-12-1
- Chemical Name:
- DBCO-PEG4-NH-Boc
- Synonyms
- DBCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-NH-Boc;DBCO-NHCO-PEG4-t-Boc Amine;5,8,11,14-Tetraoxa-2,18-diazaheneicosanoic acid, 21-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-17,21-dioxo-, 1,1-dimethylethyl ester
- CBNumber:
- CB23373604
- Molecular Formula:
- C34H45N3O8
- Molecular Weight:
- 623.74
- MDL Number:
- MFCD30730371
- MOL File:
- 1255942-12-1.mol
DBCO-PEG4-NH-Boc Chemical Properties,Uses,Production
Description
DBCO-NHCO-PEG4-NH-Boc is a click chemistry reagent. it can undergo copper-free Click Chemistry reactions with azides. The Boc protecting group can be removed under acidic conditions.
Biological Activity
DBCO-NHCO-PEG4-NH-Boc is a PROTAC linker that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).
in vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
target
| Cleavable
| PEGs
| Alkyl/ether
|
DBCO-PEG4-NH-Boc Preparation Products And Raw materials
Raw materials
Preparation Products
DBCO-PEG4-NH-Boc Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 +86-15680926068 | 1924344760@confluore.cn | China | 2996 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Shanghai Send Pharmaceutical Technology Co., Ltd. | 021-58088081 Q3252066219 | danping@shsendpharm.com | China | 3117 | 55 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 18892239720 | psaitong@jm-bio.com | China | 12308 | 58 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4824 | 58 |
| Shaanxi Xinyan Bomei Biotechnology Co., Ltd. | 029-86217788 13892832556 | 2440688701@qq.com | China | 1992 | 58 |
| Changzhou Kechem Bio-Scientific Co., LTD. | 0519-68985668 13685222090 | sales@kechem.cn | China | 26033 | 58 |
View Lastest Price from DBCO-PEG4-NH-Boc manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-03-20 | DBCO-NHCO-PEG4-NHBoc
1255942-12-1
|
US $0.00 / mg | 50mg | >95.00% | 250mg | Xian confluore Biological Technology Co., Ltd. |
-
- DBCO-NHCO-PEG4-NHBoc
1255942-12-1
- US $0.00 / mg
- >95.00%
- Xian confluore Biological Technology Co., Ltd.