261766-73-8
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- CAS号:
- 261766-73-8
- 英文名:
- 5-HT4 antagonist 1
- 英文别名:
- 5-HT4 antagonist 1;1,4-Benzodioxin-5-carboxamide, 2,3-dihydro-N-[[1-[3-[(4-methyl-1-piperazinyl)sulfonyl]propyl]-4-piperidinyl]methyl]-;inhibit,5-HT4 antagonist 1,5-hydroxytryptamine Receptor,Serotonin Receptor,5-HT Receptor,5 HT4 antagonist 1,5-HT-4 antagonist 1,Inhibitor,5HT4 antagonist 1
- 中文名:
- 261766-73-8
- 中文别名:
- 化合物 T10169;化合物5-HT4 ANTAGONIST 1
- CBNumber:
- CB24797018
- 分子式:
- C23H36N4O5S
- 分子量:
- 480.62
- MOL File:
- 261766-73-8.mol
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261766-73-8化学性质
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密度:
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1.31±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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形态:
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Solid
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酸度系数(pKa):
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14.39±0.20(Predicted)
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颜色:
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Light brown to brown
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261766-73-8性质、用途与生产工艺
5-HT4 antagonist 1 是一个 5-HT4 受体拮抗剂， 其 pKi 值为 9.6。
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5-HT
4
Receptor
9.6 (pKi)
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5-HT4 antagonist 1 (compound 6b) is a 5-HT
4
receptor antagonist with a pK
i
of 9.6.
5-HT4 antagonist 1 (compound 6b) demonstrates good exposure and prolongs t
1/2
in other species, including the mouse (t
1/2
7 h), rat (t
1/2
12 h) and mini-pig (t
1/2
21 h). In Phase I clinical trial, it is found that 5-HT4 antagonist 1 has good oral bioavailability with a steady state plasma t
1/2
of >100 h.
261766-73-8
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-100170 | 5-HT4 antagonist 1 | | 1 mg | 960元 |
| 2024/04/30 | HY-100170 | 5-HT4 antagonist 1 | | 5 mg | 2400元 |
261766-73-8, 261766-73-8 相关搜索:
- 化合物5-HT4 ANTAGONIST 1
- 化合物 T10169
- 261766-73-8
- inhibit,5-HT4 antagonist 1,5-hydroxytryptamine Receptor,Serotonin Receptor,5-HT Receptor,5 HT4 antagonist 1,5-HT-4 antagonist 1,Inhibitor,5HT4 antagonist 1
- 1,4-Benzodioxin-5-carboxamide, 2,3-dihydro-N-[[1-[3-[(4-methyl-1-piperazinyl)sulfonyl]propyl]-4-piperidinyl]methyl]-
- 5-HT4 antagonist 1