蛇孢菌素A
|
|
- CAS号:
- 4611-05-6
- 英文名:
- OPHIOBOLIN A
- 英文别名:
- ophiobolin;cochliobolin;OPHIOBOLIN A;COCHLIOBOLIN A;Ophiobolin A >=95% (HPLC);Ophiobolin A (Cochliobolin A);Ophiobolin, Helminthosporium sp.;Cochliobolin A, Ophiobolin, Ophiobalin;ophiobolin A from helminthosporium sp.;18-epoxy-3-hydroxy-5-oxo-19-dien-25-a(18r)-ophiobola-14
- 中文名:
- 蛇孢菌素A
- 中文别名:
- 蛇孢菌素;蛇孢菌素A;化合物 OPHIOBOLIN A
- CBNumber:
- CB2735485
- 分子式:
- C25H36O4
- 分子量:
- 400.55
- MOL File:
- 4611-05-6.mol
|
|
|
蛇孢菌素A化学性质
-
熔点:
-
182°C
-
|
-
沸点:
-
443.19°C (rough estimate)
-
|
-
密度:
-
1.0278 (rough estimate)
-
|
-
折射率:
-
1.4460 (estimate)
-
|
-
储存条件:
-
2-8°C
-
|
-
溶解度:
-
Soluble in DMSO (up to 10 mg/ml)
-
|
-
形态:
-
White to off-white solid.
-
|
-
酸度系数(pKa):
-
13.84±0.70(Predicted)
-
|
-
颜色:
-
White
-
|
-
稳定性:
-
Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 2 months.
-
|
蛇孢菌素A性质、用途与生产工艺
蛇孢菌素A(OphA)是一种由双极霉属真菌产生的二倍半萜化合物,已被证实在多种实体瘤中具有抗癌效应,但其在直肠癌中的作用尚不明确。
Ophiobolin A 是一种真菌代谢产物和植物毒素,是一种有效的、不可逆的钙调素激活环核苷酸磷酸二酯酶的抑制剂,其IC50 值为 9 μM。Ophiobolin A 具有抗菌和抗癌作用。
IC50: 9 μM (calmodulin-activated cyclic nucleotide phosphodiesterase).
蛇孢菌素A
上下游产品信息
上游原料
下游产品
4611-05-6, 蛇孢菌素A 相关搜索:
- 抑制剂
- 药靶配体
- 化工原料
- 微生物代谢物
- Intracellular Calcium Signaling
- BioChemical
- Cell Biology
- Calcium Antagonists
- Cell Signaling and Neuroscience
- C25H36O4
- 化合物 OPHIOBOLIN A
- 蛇孢菌素
- 蛇孢菌素A
- 4611-05-6
- Ophiobolin A (Cochliobolin A)
- Ophiobolin A >=95% (HPLC)
- Spiro[dicyclopenta[a,d]cyclooctene-3(2H),2'(3'H)-furan]-6-carboxaldehyde, 1,3a,4,4',5',6a,7,8,9,9a,10,10a-dodecahydro-9-hydroxy-3',9,10a-trimethyl-5'-(2-methyl-1-propen-1-yl)-7-oxo-, (2'S,3'S,3aR,5'R,6aS,9R,9aS,10aR)-
- OPHIOBOLIN A
- Cochliobolin A, Ophiobolin, Ophiobalin
- (18R)-3-Hydroxy-5-oxo-14,18-epoxyophiobola-7,19-diene-25-al
- (18R)-14,18-Epoxy-3-hydroxy-5-oxoophiobola-7,19-dien-25-al
- Ophiobolin, Helminthosporium sp.
- ophiobolin A from helminthosporium sp.
- COCHLIOBOLIN A
- ophiobolin
- cochliobolin
- 18-epoxy-3-hydroxy-5-oxo-19-dien-25-a(18r)-ophiobola-14