AMY-101 ACETATE
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- CAS号:
- 英文名:
- AMY-101 acetate
- 英文别名:
- AMY-101 acetate
- 中文名:
- AMY-101 ACETATE
- 中文别名:
- CBNumber:
- CB29019823
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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AMY-101 ACETATE化学性质
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形态:
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Solid
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颜色:
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White to off-white
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AMY-101 ACETATE性质、用途与生产工艺
AMY-101 acetate (Cp40 acetate) 是补体 C3 的肽类抑制剂 (KD = 0.5 nM)，可抑制非人类灵长类动物自然发生的牙周炎。AMY-101 acetate (Cp40 acetate) 在 COVID-19 重症肺炎合并全身超炎症模型中具有良好的抗炎活性。
AMY-101 can improve the periodontal condition of NHPs with natural chronic periodontitis.
AMY-101 can induce a long-lasting anti-inflammatory effect.
AMY-101 (4 mg/kg bodyweight, subcutaneous injection. once per 24 hr for a total of 28 days) causes a significant and long-lasting reduction in PPD, an index that measures tissue destruction.
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Animal Model:
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Fifteen adult male cynomolgus monkeys (Macaca fascicularis) (7-15 years old; 5.0-7.6 kg body weight).
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Dosage:
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0.1 mg/site; 50 μL of 2 mg/mL solution.
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Administration:
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Injected locally. (Either three times per week or once a week for 6 weeks followed by a 6-week follow-up period without treatment.)
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Result:
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Does not cause irritation in healthy gingiva.
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AMY-101 ACETATE
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AMY-101 ACETATE 试剂级价格
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-P1717B | AMY-101 acetate | | 1mg | 3700元 |
| 2024/08/19 | HY-P1717B | AMY-101 acetate | | 5mg | 9100元 |