奥沙奈坦
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- CAS号:
- 160492-56-8
- 英文名:
- Osanetant
- 英文别名:
- SR142801;SR-142801;Osanetant;Osanetant >=98% (HPLC);N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide;(R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine;N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide;AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-;Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
- 中文名:
- 奥沙奈坦
- 中文别名:
- 奥沙奈坦;化合物 T16408;化合物 OSANETANT
- CBNumber:
- CB31179397
- 分子式:
- C35H41Cl2N3O2
- 分子量:
- 606.62
- MOL File:
- 160492-56-8.mol
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奥沙奈坦化学性质
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沸点:
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727.9±60.0 °C(Predicted)
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密度:
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1.25
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储存条件:
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-20°C
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溶解度:
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DMSO: soluble15mg/mL, clear
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形态:
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powder
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酸度系数(pKa):
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8.33±0.10(Predicted)
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颜色:
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white to beige
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旋光性 (optical activity):
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[α]/D +18 to +24°, c = 1 in methanol
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奥沙奈坦性质、用途与生产工艺
Osanetant (SR142801) 是一种选择性的 NK3 受体拮抗剂。Osanetant 有抗焦虑和抗抑郁的作用，并被研究用于精神分裂症。
Osanetant (SR142801; po; 1-10 mg/kg; 60 min before testing) significantly increases social interaction time.
Osanetant (ip; 5 and 10 mg/kg; 30 min before testing) decreases immobility time.
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Animal Model:
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Male Mongolian gerbils of 7 weeks old (50-60 g)
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Dosage:
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1, 3 and 10 mg/kg
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Administration:
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Po; 60 min before testing
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Result:
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Significantly increased social interaction time.
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奥沙奈坦
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-14551 | 奥沙奈坦
Osanetant | 160492-56-8 | 1mg | 2320元 |
| 2024/11/08 | HY-14551 | 奥沙奈坦
Osanetant | 160492-56-8 | 5mg | 5800元 |
160492-56-8, 奥沙奈坦 相关搜索:
- 抑制剂
- C35H41Cl2N3O2
- 化合物 OSANETANT
- 化合物 T16408
- 奥沙奈坦
- 160492-56-8
- Osanetant >=98% (HPLC)
- N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]propyl]-4-phenylpiperidin-4-yl]-N-methylacetamide
- Osanetant AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
- SR-142801
- SR142801
- (R)-N-{{3-[1-Benzoyl-3-(3,4-dichlorophenyl)piperidin-3-yl]prop-1-yl}-4-phenylpiperidin-4-yl}-N-methylacetamine
- N-[1-[3-[(3R)-1-Benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-methylacetamide
- AcetaMide, N-[1-[3-[(3R)-1-benzoyl-3-(3,4-dichlorophenyl)-3-piperidinyl]propyl]-4-phenyl-4-piperidinyl]-N-Methyl-
- Osanetant