木聚硫钠
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- CAS号:
- 140207-93-8
- 英文名:
- Pentosan
- 英文别名:
- Cb 8061;Hemoclar;Cartrophen;Hemoclar [french];Pentosan Polysulfate Sodium (W/W 43%);beta-D-Xylan, (1-4), 2,3-bis(hydrogen sulfate), sodium salt;4-o-Methyl-alpha-D-glucurono-beta-D-xylan, hydrogen sulfate, sodium salt
- 中文名:
- 木聚硫钠
- 中文别名:
- 戊聚糖多硫酸酯钠;化合物 T12420L
- CBNumber:
- CB31179463
- 分子式:
- 分子量:
- 0
- MOL File:
- Mol file
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木聚硫钠化学性质
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储存条件:
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4°C, sealed storage, away from moisture
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形态:
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Solid
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颜色:
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White to off-white
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木聚硫钠性质、用途与生产工艺
Pentosan Polysulfate Sodium 是一种口服生物可利用的半合成药物，具有抗炎和促软骨生成的特性。Pentosan Polysulfate Sodium 也是一种有效和选择性的抗 HIV 药物。Pentosan Polysulfate Sodium 用于间质性膀胱炎的研究。
Pentosan Polysulfate Sodium has been shown to inhibit HIV-1 activity with an ED
50
of 0.19 μg/mL in MT-4 cells. It inhibits HIV-1 antigen expression in HUT-78 cells at an ED
50
of 0.02 μg/mL, and complete inhibition of HIV-1 antigen expression is obtained at a concentration of 4.0 μg/mL.
Pentosan Polysulfate Sodium suppresses NF-κB, decreases the proinflammatory actions of TNFα, and decreases high glucose and advanced glycation end products (AGEs) stimulated MCP-1 production.
Pentosan Polysulfate Sodium has been shown to decreases interstitial inflammation and glomerulosclerosis in 5/6 nephrectomized rats. Pentosan polysulfate treatment preserves renal function, significantly reduces albuminuria, and markedly decreases the severity of renal lesions, including tubulointerstitial inflammation. Pentosan Polysulfate Sodium also reduces upregulation of TNFα and proinflammatory genes in aging diabetic kidneys.
木聚硫钠
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-A0203A | Pentosan Polysulfate Sodium (W/W 43%) | | 1 mg | 225元 |
| 2024/11/08 | HY-A0203A | Pentosan Polysulfate Sodium (W/W 43%) | | 5 mg | 450元 |
140207-93-8, 木聚硫钠 相关搜索:
- 戊聚糖多硫酸酯钠
- 化合物 T12420L
- 140207-93-8
- Pentosan Polysulfate Sodium (W/W 43%)
- Hemoclar [french]
- Hemoclar
- Cb 8061
- Cartrophen
- beta-D-Xylan, (1-4), 2,3-bis(hydrogen sulfate), sodium salt
- 4-o-Methyl-alpha-D-glucurono-beta-D-xylan, hydrogen sulfate, sodium salt