APTSTAT3-9R
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- CAS号:
- 英文名:
- APTSTAT3-9R
- 英文别名:
- APTSTAT3-9R
- 中文名:
- APTSTAT3-9R
- 中文别名:
- 结合肽APTSTAT3-9R
- CBNumber:
- CB34929096
- 分子式:
- C223H330N80O51
- 分子量:
- 0
- MOL File:
- Mol file
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APTSTAT3-9R化学性质
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形态:
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Solid
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颜色:
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White to off-white
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APTSTAT3-9R性质、用途与生产工艺
APTSTAT3-9R 是一种特定的 STAT3 结合肽，通过特异性阻断 STAT3 磷酸化来抑制 STAT3 激活和下游信号传导。APTSTAT3-9R 具有抗增殖作用和抗肿瘤活性。
APTSTAT3-9R (7.5, 15, and 30 μmol/L; 6 hours) significantly reduces STAT3–DNA-binding activity in a dose-dependent manner in human lung carcinoma cells (A549).
APTSTAT3-9R (30 μM; for 2 weeks) suppresses cell viability and proliferation of cancer cells and significantly suppresses colony formation. APTSTAT3-9R has IC50s of 10 to 20 μM in A549, B16F1 and HepG2 cells.
APTSTAT3-9R (7.5, 15, and 30 μmol/L; 6 hours) effectively inhibits phosphorylation of STAT3 but does not affect the level of AKT phosphorylation, indicating specificity of the aptide.
APTSTAT3-9R (8 mg/kg in 50 μL; intratumorally injected every other day for a total of four injections) suppresses tumor growth in 6-week-old female BALB/c nude mice with A549 cells.
APTSTAT3-9R
上下游产品信息
上游原料
下游产品
APTSTAT3-9R 试剂级价格
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/08/19 | HY-P2282 | APTSTAT3-9R
APTSTAT3-9R | | 1 mg | 1500元 |
| 2024/08/19 | HY-P2282 | APTSTAT3-9R
APTSTAT3-9R | | 5 mg | 4500元 |
APTSTAT3-9R 相关搜索:
- 目录肽
- C223H330N80O51
- 结合肽APTSTAT3-9R
- APTSTAT3-9R