根赤壳菌素
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- CAS号:
- 12772-57-5
- 英文名:
- RADICICOL
- 英文别名:
- KF9-A;KF58332;FO-4910;MONORDEN;RADICICOL;RADISICOL;RHI-12648;MONORODENE;monorderne;Nsc 294404
- 中文名:
- 根赤壳菌素
- 中文别名:
- 根赤壳菌素;根赤壳霉素;单孢菌素 A
- CBNumber:
- CB4165202
- 分子式:
- C18H17ClO6
- 分子量:
- 364.78
- MOL File:
- 12772-57-5.mol
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根赤壳菌素化学性质
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熔点:
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193.5°
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比旋光度:
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D20 +203° (chloroform)
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沸点:
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656.2±55.0 °C(Predicted)
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密度:
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1.364±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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ethanol: 10 mg/mL
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形态:
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solid
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酸度系数(pKa):
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6.29±0.40(Predicted)
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颜色:
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yellow
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稳定性:
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Stable for 2 years from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20°C for up to 1 month.
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根赤壳菌素性质、用途与生产工艺
Radicicol 是 Hsp90 的抑制剂，IC50 值为 1 μM。Radicicol 靶向 Hsp90，与 Hsp90 的 ATP 酶结构域结合并阻止 Hsp90 蛋白成熟，导致蛋白酶体降解。Radicicol 是一种具有抗疟疾活性的抗真菌抗生素 (antifungal antibiotic)，通过靶向恶性疟原虫拓扑异构酶 VIB 来削弱线粒体复制。
根赤壳菌素
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-N6769 | 根赤壳菌素
Radicicol | 12772-57-5 | 1mg | 1950元 |
| 2024/01/25 | HY-N6769 | 根赤壳菌素
Radicicol | 12772-57-5 | 5mg | 8350元 |
根赤壳菌素
生产厂家
全球有 148家供应商
根赤壳菌素国内生产厂家
12772-57-5, 根赤壳菌素 相关搜索:
- Heat Shock Protein 90
- antibiotic
- 抗生素
- 微生物代谢物
- 生化试剂
- BioChemical
- Antibiotics A to Z
- Antibiotics N-S
- Antibiotics
- C18H17O6Cl
- 12772-54-5
- 单孢菌素 A
- 根赤壳菌素
- 根赤壳霉素
- 12772-57-5
- adricicol.
- RADICICOL USP/EP/BP
- Monorden A
- Radicicol, Diheterospora chlamydosporia - CAS 12772-57-5 - Calbiochem
- 6H-Oxireno[e][2]benzoxacyclotetradecin-6,12(7H)-dione,8-chloro-1a,14,15,15a-tetrahydro-9,11-dihydroxy-14-methyl-,(1aR,2Z,4E,14R,15aR)-
- Nsc 294404
- 6H-Oxireno(E)(2)benzoxacyclotetradecin-6,12(7H)-dione, 8-chloro-1A,14,15,15A-tetrahydro-9,11-dihydroxy-14-methyl-
- 5-chloro-6-(7,8-epoxy-10-hydroxy-2-oxo-3,5-undecadienyl)-beta-resorcylic acid mu-lactone, KF58332, KF9-A, Monorden, Radisicol, Monorodene, RHI-12648, FO-4910
- radicicol from diheterospora chlamydosporia
- Radicicol,Monorden
- monorderne
- 6h-oxireno(e)(2)benzoxacyclotetradecin-6,12(7h)-dione,8-chloro-1a,14,15,15a-te
- 11-dihydroxy-14-methyl-trahydro-
- RHI-12648
- RADICICOL, HUMICOLA FUSCOATRA
- RADICICOL, DIHETEROSPORA CHLAMYDOSPORIA
- RADICICOL
- RADISICOL
- MONORODENE
- MONORDEN
- KF9-A
- KF58332
- FO-4910
- 5-CHLORO-6-(7,8-EPOXY-10-HYDROXY-2-OXO-3,5-UNDECADIENYL)-BETA-RESORCYLIC ACID MU-LACTONE
- [1AS-(1AR*,2Z,4E,14*,15AR*)]-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE
- (1AR,2Z,4E,14R,15AR)-8-CHLORO-1A,14,15,15A-TETRAHYDRO-9,11-DIHYDROXY-14-METHYL-6H-OXIRENO[E][2]BENZOXACYCLOTETRADECIN-6,12(7H)-DIONE