AURORA KINASE INHIBITOR III
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- CAS号:
- 879127-16-9
- 英文名:
- Aurora Kinase Inhibitor III
- 英文别名:
- AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
- 中文名:
- AURORA KINASE INHIBITOR III
- 中文别名:
- 极光激酶抑制剂III;化合物AURORA KINASE INHIBITOR III;N-(3-((4-((3-(三氟甲基)苯基)氨基)嘧啶-2-基)氨基)苯基)环丙烷甲酰胺
- CBNumber:
- CB42098016
- 分子式:
- C21H18F3N5O
- 分子量:
- 413.4
- MOL File:
- 879127-16-9.mol
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AURORA KINASE INHIBITOR III化学性质
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密度:
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1.456±0.06 g/cm3(Predicted)
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储存条件:
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2-8°C
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溶解度:
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H2O: <2mg/mL
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酸度系数(pKa):
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14.51±0.70(Predicted)
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形态:
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White solid
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颜色:
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white
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AURORA KINASE INHIBITOR III性质、用途与生产工艺
Aurora kinase inhibitor III是有效的Aurora A kinase抑制剂，IC50为42 nM。它对BMX, BTK, IGF-1R, c-Src, TRKB, SYK和EGFR分别为386, 3550, 591, 1980, 2510, 887和>10,000 nM。
| Target | Value |
Aurora A
(Cell-free assay)
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42 nM
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BMX
(Cell-free assay)
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386 nM
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IGF-1R
(Cell-free assay)
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591 nM
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SYK
(Cell-free assay)
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887 nM
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c-Src
(Cell-free assay)
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1980 nM
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AURORA KINASE INHIBITOR III
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-112373 | AURORA KINASE INHIBITOR III
Aurora kinase inhibitor-3 | 879127-16-9 | 1mg | 855元 |
| 2024/11/08 | HY-112373 | AURORA KINASE INHIBITOR III
Aurora kinase inhibitor-3 | 879127-16-9 | 5mg | 1500元 |
AURORA KINASE INHIBITOR III
生产厂家
879127-16-9, AURORA KINASE INHIBITOR III 相关搜索:
- 合成有机化合物配体
- 抑制剂
- N-(3-((4-((3-(三氟甲基)苯基)氨基)嘧啶-2-基)氨基)苯基)环丙烷甲酰胺
- 极光激酶抑制剂III
- 化合物AURORA KINASE INHIBITOR III
- 879127-16-9
- Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
- N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide
- AKI-7169(Aurora Kinase Inhibitor III)
- Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid
- Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-
- Aurora Kinase Inhibitor 3
- Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
- AKI-7169
- N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
- Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
- Aurora Kinase Inhibitor III