Aurora Kinase Inhibitor III

Aurora  Kinase  Inhibitor  III Struktur
879127-16-9
CAS-Nr.
879127-16-9
Englisch Name:
Aurora Kinase Inhibitor III
Synonyma:
AKI-7169;Aurora Kinase Inhibitor 3;Aurora Kinase Inhibitor III;AKI-7169(Aurora Kinase Inhibitor III);Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem;N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide;N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide;Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-;Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide;Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
CBNumber:
CB42098016
Summenformel:
C21H18F3N5O
Molgewicht:
413.4
MOL-Datei:
879127-16-9.mol

Aurora Kinase Inhibitor III Eigenschaften

Dichte
1.456±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
Löslichkeit
H2O: <2mg/mL
pka
14.51±0.70(Predicted)
Aggregatzustand
White solid
Farbe
white

Sicherheit

WGK Germany  3

Aurora Kinase Inhibitor III Chemische Eigenschaften,Einsatz,Produktion Methoden

Allgemeine Beschreibung

A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC50 = 131, 386, 591, and 887 nM, respectively).

Biochem/physiol Actions

Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively

Aurora Kinase Inhibitor III Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte


Aurora Kinase Inhibitor III Anbieter Lieferant Produzent Hersteller Vertrieb Händler.

Global( 47)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795
ivan@atkchemical.com China 32820 60
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000
marketing@targetmol.com United States 32063 58
Zhejiang J&C Biological Technology Co.,Limited
+1-2135480471 +1-2135480471
sales@sarms4muscle.com China 10473 58
InvivoChem
+1-708-310-1919 +1-13798911105
sales@invivochem.cn United States 6391 58
TargetMol Chemicals Inc.

support@targetmol.com United States 38463 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525
masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181
sales@aladdinsci.com United States 57505 58
Sigma-Aldrich 021-61415566 800-8193336
orderCN@merckgroup.com China 51456 80
Shanghai Lollane Biological Technology Co.,Ltd. 021-52996696,15000506266 15000506266
China 4456 55
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465
sales@zehanbiopharma.com China 1008 55

  • Aurora Kinase Inhibitor III
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide
  • N-[3-[[4-[3-(trifluoromethyl)anilino]pyrimidin-2-yl]amino]phenyl]cyclopropanecarboxamide
  • AKI-7169
  • Aurora Kinase Inhibitor III - CAS 879127-16-9 - Calbiochem
  • Aurora Kinase Inhibitor 3
  • Cyclopropanecarboxamide, N-[3-[[4-[[3-(trifluoromethyl)phenyl]amino]-2-pyrimidinyl]amino]phenyl]-
  • Cyclopropanecarboxylic acid {3-[4-(3-trifluoromethyl-phenylamino)-pyrimidin-2-ylamino]-phenyl}-amide >=98% (HPLC), solid
  • AKI-7169(Aurora Kinase Inhibitor III)
  • N-(3-((4-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-2-yl)amino)phenyl)cyclopropanecarboxamide
  • Aurora Kinase,Aurora kinase inhibitor 3,Aurora kinase inhibitor3,Inhibitor,Aurora kinase inhibitor-3,inhibit
  • 879127-16-9
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