Aurora Kinase Inhibitor III Chemische Eigenschaften,Einsatz,Produktion Methoden
Allgemeine Beschreibung
A cell-permeable 2,4-dianilinopyrimidine compound that acts as an ATP-competitive, potent, but non-selective inhibitor of Aurora A (IC
50 = 42 nM). At higher concentrations, also inhibits the activities of other kinases, such as Lck, Bmx, IGF-1R, and Syk (IC
50 = 131, 386, 591, and 887 nM, respectively).
Biochem/physiol Actions
Target IC50: 42 nM against Aurora A; 131, 386, 591, and 887 nM, against Lck, Bmx, IGF-1R, and Syk , respectively
Aurora Kinase Inhibitor III Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte