CID-2011756
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- CAS号:
- 638156-11-3
- 英文名:
- CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide
- 英文别名:
- CID 2011756;CID-20°C11756;CID-2011756, >97%;CID-2011756, >=98%;CID2011756; CID-2011756;5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide;5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide;5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide;5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide;2-Furancarboxamide, 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-
- 中文名:
- CID-2011756
- 中文别名:
- CID-20°C11756;化合物 CID-2011756;PKD1抑制剂(CID 2011756);5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-甲酰胺;5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-羧酰胺;5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-羧酰胺;5-(3-氯苯基)-N-(4-(吗啉代甲基)苯基)呋喃-2-甲酰胺;5-(3-氯苯基)-N-[4-(4-吗啉基甲基)苯基]-2-呋喃甲酰胺;5-(3-氯苯基)-N-[4-(4-吗啉基甲基)苯基]-2-呋喃甲酰胺(CID-2011756)
- CBNumber:
- CB42642194
- 分子式:
- C22H21ClN2O3
- 分子量:
- 396.87
- MOL File:
- 638156-11-3.mol
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CID-2011756化学性质
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沸点:
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491.0±45.0 °C(Predicted)
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密度:
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1.297±0.06 g/cm3(Predicted)
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储存条件:
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room temp
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溶解度:
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DMSO: soluble10mg/mL (clear solution)
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形态:
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powder
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酸度系数(pKa):
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12.54±0.70(Predicted)
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颜色:
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white to beige
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稳定性:
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Stable for 1 year from date of purchase as supplied. Solutions in DMSO or ethanol may be stored at -20° for up to 3 months.
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CID-2011756性质、用途与生产工艺
CID 2011756是protein kinase D (PKD)的抑制剂，对PKD1、PKD2、PKD3的IC50值分别为3.2、0.6和0.7 μM。
| Target | Value |
PKD2
()
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0.6 μM
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PKD3
()
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0.7 μM
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PKD1
()
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3.2 μM
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CID 2011756 is an ATP-competitive PKD1 inhibitor, with an IC
50
of 3.2 µM. CID 2011756 decreases the phosphorylation of endogenous PKD1 Ser
916
in LNCaP cancer cells with an EC
50
of 10±0.7 µM. CID 2011756 also has cellular pan-PKD inhibitory effects, with IC
50
s of 0.6±0.1 µM and 0.7±0.2 µM for PKD2 and PKD3, respectively.
CID-2011756
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-13454 | CID-2011756
CID 2011756 | 638156-11-3 | 5mg | 500元 |
| 2024/11/08 | HY-13454 | CID-2011756
CID 2011756 | 638156-11-3 | 10mM * 1mLin DMSO | 550元 |
638156-11-3, CID-2011756 相关搜索:
- Inhibitors
- 抑制剂
- 天然产物
- 细胞生物学试剂
- 信号转导通路激酶抑制剂
- 小分子抑制剂，天然产物
- 小分子抑制剂
- 5-(3-氯苯基)-N-(4-(吗啉代甲基)苯基)呋喃-2-甲酰胺
- 化合物 CID-2011756
- CID-20°C11756
- 5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-甲酰胺
- 5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-羧酰胺
- 5-(3-氯苯基)-N-(4-(吗啉甲基)苯基)呋喃-2-羧酰胺
- PKD1抑制剂(CID 2011756)
- 5-(3-氯苯基)-N-[4-(4-吗啉基甲基)苯基]-2-呋喃甲酰胺(CID-2011756)
- 5-(3-氯苯基)-N-[4-(4-吗啉基甲基)苯基]-2-呋喃甲酰胺
- 638156-11-3
- CID-20°C11756
- 2-Furancarboxamide, 5-(3-chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-
- CID-2011756, >97%
- CID2011756; CID-2011756
- CID-2011756, >=98%
- 5-(3-Chlorophenyl)-N-[4-(morpholin-4-ylmethyl)phenyl]furan-2-carboxamide
- CID 2011756
- CID-2011756,5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide
- 5-(3-Chlorophenyl)-N-[4-(4-morpholinylmethyl)phenyl]-2-furancarboxamide
- 5-(3-Chlorophenyl)-N-[4-morpholin-4-ymethyl)phenyl]furan-2-carboxamide
- 5-(3-chlorophenyl)-N-(4-(MorpholinoMethyl)phenyl)furan-2-carboxaMide