1-acetyl-3,2-toluyl-5-fluorouracil
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- CAS号:
- 71861-76-2
- 英文名:
- 1-acetyl-3,2-toluyl-5-fluorouracil
- 英文别名:
- A-?OT-?Fu;1-Acetyl-3-o-toluyl-5-fluorouracil;1-acetyl-3,2-toluyl-5-fluorouracil;1 Acetyl 3 o toluyl 5 fluorouracil,1Acetyl3otoluyl5fluorouracil;2,4(1H,3H)-Pyrimidinedione, 1-acetyl-5-fluoro-3-(2-methylbenzoyl)-
- 中文名:
- 1-acetyl-3,2-toluyl-5-fluorouracil
- 中文别名:
- 化合物 T10013
- CBNumber:
- CB51367983
- 分子式:
- C14H11FN2O4
- 分子量:
- 290.25
- MOL File:
- 71861-76-2.mol
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1-acetyl-3,2-toluyl-5-fluorouracil化学性质
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熔点:
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141-143 °C(Solv: ethyl ether (60-29-7))
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沸点:
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408.8±55.0 °C(Predicted)
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密度:
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1.44±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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-5.29±0.40(Predicted)
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1-acetyl-3,2-toluyl-5-fluorouracil性质、用途与生产工艺
1-Acetyl-3-o-toluyl-5-fluorouracil是有效的抗肿瘤剂。
Oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil demonstrates a remarkable effect on MH134 solid tumors, the effect being more marked than that of subcutaneous administration of 1-Acetyl-3-o-toluyl-5-fluorouracil. Anti-tumor activity of oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at a dose of 0.2 mmol/kg/d is comparable to that of subcutaneous administration of 5-fluorouracil at the same dose. The level of decrease in thymus weight and the magnitude of increase of spleen weight following oral administration of 1-Acetyl-3-o-toluyl-5-fluorouracil at any dose are smaller than those by subcutaneous administration of 5-fluorouracil (0.2 mmol/kg/d).
1-acetyl-3,2-toluyl-5-fluorouracil
上下游产品信息
上游原料
下游产品
1-acetyl-3,2-toluyl-5-fluorouracil
生产厂家
71861-76-2, 1-acetyl-3,2-toluyl-5-fluorouracil 相关搜索:
- 化合物 T10013
- 71861-76-2
- 1 Acetyl 3 o toluyl 5 fluorouracil,1Acetyl3otoluyl5fluorouracil
- 2,4(1H,3H)-Pyrimidinedione, 1-acetyl-5-fluoro-3-(2-methylbenzoyl)-
- A-?OT-?Fu
- 1-Acetyl-3-o-toluyl-5-fluorouracil
- 1-acetyl-3,2-toluyl-5-fluorouracil