PHA-543613 Dihydrochloride
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- CAS号:
- 478148-58-2
- 英文名:
- PHA-543613 Dihydrochloride
- 英文别名:
- PHA 543613E;PHA-543613 Dihydrochloride;PHA-543613 Dihydrochloride
DISCONTINUED;N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxaMide Dihydrochloride
- 中文名:
- PHA-543613 Dihydrochloride
- 中文别名:
- CBNumber:
- CB52545557
- 分子式:
- C15H17N3O2
- 分子量:
- 271.31438
- MOL File:
- 478148-58-2.mol
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PHA-543613 Dihydrochloride化学性质
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熔点:
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>300?C
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储存条件:
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Refrigerator
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溶解度:
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DMSO, Methanol
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形态:
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Solid
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颜色:
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Tan
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PHA-543613 Dihydrochloride性质、用途与生产工艺
用途
PHA-543613 is a potent selective α7 nAChR agonist. Nicotinic acetylcholine receptors are ligand-gated ion channels activated by nicotine, expressed in multiple tissues, with high functional expression
in brain. The homomeric subtype α7 is a potential therapeutic target for cognitive deficits in schizophrenia and Alzheimer鈥瞫 disease. PHA-543613 is active in both in vitro (binding, calcium flux, pat
ch-clamp) and in vivo (auditory gating, novel object recognition) assays.
PHA-543613 Dihydrochloride
上下游产品信息
上游原料
下游产品
PHA-543613 Dihydrochloride
生产厂家
478148-58-2, PHA-543613 Dihydrochloride 相关搜索:
- Pharmaceuticals
- Pfizer compounds
- Intermediates & Fine Chemicals
- Inhibitors
- Heterocycles
- Amines
- 478148-58-2
- PHA-543613 Dihydrochloride
DISCONTINUED
- PHA 543613E
- N-[(3R)-1-Azabicyclo[2.2.2]oct-3-yl]furo[2,3-c]pyridine-5-carboxaMide Dihydrochloride
- PHA-543613 Dihydrochloride