15-O-乙酰脱氧瓜萎镰菌醇
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- CAS号:
- 88337-96-6
- 英文名:
- 15-ACETOXY-3ALPHA,7ALPHA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-EN-8-ONE
- 英文别名:
- 15-ADON;15-ACDON;3-D3-ACDON;15-acetyl-;15-Acetyl-DON;DON-15-acetate;15-ACETYLVOMITOXIN;15-ACETYLDEOXYNIVALENOL;Deoxynivalenol 15-acetyl;Deoxynivalenol 15-Acetate
- 中文名:
- 15-O-乙酰脱氧瓜萎镰菌醇
- 中文别名:
- 化合物 T10045;15-乙酰脱氧瓜萎镰菌醇;15--乙酰脱氧瓜萎廉菌醇;15-乙酰脱氧雪腐镰刀菌醇;15-乙酰脱氧雪腐镰刀菌烯醇;15-O-乙酰脱氧瓜萎镰菌醇;15-乙酰基脱氧雪腐镰刀菌烯醇;15-乙酰脱氧瓜萎镰菌醇 溶液;15-乙酰基脱氧雪腐镰刀菌烯醇溶液;15-O-乙酰基-4-脱氧瓜萎镰菌醇
- CBNumber:
- CB5435409
- 分子式:
- C17H22O7
- 分子量:
- 338.35
- MOL File:
- 88337-96-6.mol
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15-O-乙酰脱氧瓜萎镰菌醇化学性质
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沸点:
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538.6±50.0 °C(Predicted)
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密度:
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1.42±0.1 g/cm3(Predicted)
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闪点:
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2 °C
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储存条件:
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2-8°C
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溶解度:
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Chloroform: soluble; Ethanol: soluble
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酸度系数(pKa):
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11.83±0.70(Predicted)
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形态:
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Solid
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颜色:
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White to off-white
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LogP:
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-0.400 (est)
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15-O-乙酰脱氧瓜萎镰菌醇性质、用途与生产工艺
15-O-乙酰脱氧瓜萎镰菌醇是脱氧瓜萎镰菌醇的乙酰化衍生物。脱氧萎镰菌醇 (deoxynivalenol, DON) 是一种在谷类食品中由镰刀霉菌产生的单端孢霉烯毒枝菌素, DON 具有多种生物活性, 有研究表明, DON 可通过诱导 GRP78 的降解下调细胞内GRP78 水平。
将DON（79.0mg，0.27mmol）溶解在50mL无水二氯甲烷中，加入吡啶（1 mL）和4-DMAP（约10 mg），然后逐滴加入乙酸酐（27.2 mg，0.27mmol）。将反应搅拌过夜，用20mL HCl（2N）处理，并用50毫升二氯甲烷萃取3次。用硫酸钠干燥后，过滤并蒸发溶剂。剩余的残余物进行柱色谱分离（CHCl3：MeOH = 95：5），得到15-ADON即15-O-乙酰脱氧瓜萎镰菌醇（42.0 mg，47％，）。
15-Acetyl-deoxynivalenol 是一种在谷物中发现的剧毒单端孢霉烯，对 HepG2 细胞具有毒性。
15-O-乙酰脱氧瓜萎镰菌醇
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88337-96-6, 15-O-乙酰脱氧瓜萎镰菌醇 相关搜索:
- Inhibitor
- Pharmaceuticals
- Intermediates & Fine Chemicals
- Inhibitors
- 生化试剂
- 合成
- C17D3H19O7
- C17H22O7
- 15-乙酰脱氧雪腐镰刀菌醇
- 化合物 T10045
- 15-DON (15-乙酰脱氧雪腐镰刀菌烯醇)
- 15--乙酰脱氧瓜萎廉菌醇
- 15-乙酰基脱氧雪腐镰刀菌烯醇溶液
- 15-乙酰脱氧雪腐镰刀菌烯醇 标准品
- 15-乙酰基脱氧雪腐镰刀菌烯醇
- 15-O-乙酰脱氧瓜萎镰菌醇 来源于禾谷镰刀菌
- 15-O-乙酰基-4-脱氧雪腐镰菌醇
- 15-乙酰脱氧雪腐镰刀菌烯醇
- 15-乙酰脱氧瓜萎镰菌醇
- 15-O-乙酰基-4-脱氧瓜萎镰菌醇
- 15-O-乙酰脱氧瓜萎镰菌醇溶液, 100PPM
- 15-乙酰氧基-3ALPHA,7ALPHA-二羟基-12,13-环氧单端孢霉-9-烯-8-酮
- 15-乙酰脱氧瓜萎镰菌醇 溶液
- 15-乙酰氧基-3Α,7Α-二羟基-12,13-环氧单端孢霉-9-烯-8-酮
- 15-O-乙酰脱氧瓜萎镰菌醇
- 88337-96-6
- Deoxynivalenol 15-acetyl
- 15-Acetyl-DON
- 15-Acetyl DON 100ug/ml in ACN
- Trichothec-9-en-8-one, 15-(acetyloxy)-12,13-epoxy-3,7-dihydroxy-, (3α,7α)-
- 15-Acetyl-deoxynivalenol Solution (100ug/ml Acetonitrile Solution)
- 15-Acetyldeoxynivalenol Standard
- 15-Acetyl Deoxynivalenol (~90%)
- 15-A-DON / 15-Acetylvomitoxin / 15-O-Acetyl-4-deoxynivalenol
- 15-A-DON (15-acetyl-deoxynivalenol)
- Deoxynivalenol 15-Acetate
- (3α,7α)-15-(Acetyloxy)-12,13-epoxy-3,7-dihydroxy-trichothec-9-en-8-one
- 15-acetyl-
- 15-Acetyl-deoxynivalenol 99%
- Trichothec-9-en-8-one, 15-(acetyloxy)-12,13-epoxy-3,7-dihydroxy-, (3-alpha,7-alpha)-
- DON-15-acetate
- 3α,7α-Dihydroxy-15-acetoxy-12,13-epoxytrichotheca-9-ene-8-one
- 15-Acetyl-4-deoxynivalenol
- 12,13-Epoxy-3α,7α-dihydroxy-15-acetoxytrichothec-9-en-8-one
- 15-Acetyldeoxynivalenol Solution, 100 /mL in acetonitrile, Oekanal
- 3-Acetyl-d3-deoxynivalenol solution
- 15-AcDON, 15-Acetylvomitoxin, 15-ADON, 15-Acetoxy-3alpha,7alpha-dihydroxy-12,13-epoxytrichothec-9-en-8-one
- 15-O-Acetyl-4-deoxynivalenol from Fusarium graminearum, 15-Acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one
- 15-ACETYL-DEOXYNIVALENOL SOLUTION (100&MU
- 15-o-acetyl-4-deoxynivalenol from fusarium graminearum
- 15-acetyldeoxynivalenol solution
- 15-acetoxy-3α,7α-dihydroxy-12,13-epoxytrichothec-9-en-8-one
- 15-O-ACETYL-4-DEOXYNIVALENOL FROMFUSARIU M GRAMINEA
- 15-O-acetyl-4-deoxynivalenol from*fusarium gramin
- trichothec-9-en-8-one,15-(acetyloxy)-12,13-epoxy-3,7-dihydroxy-,(3-alpha,7-al
- 15-O-ACETYL-4-DEOXYNIVALENOL
- 15-ACETOXY-3ALPHA,7ALPHA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-EN-8-ONE
- 15-ACETYLDEOXYNIVALENOL