硫平酸
|
|
- CAS号:
- 61220-69-7
- 英文名:
- Tiopinac
- 英文别名:
- Tiopinac;RS 40974;Dibenzo[b,e]thiepin-3-acetic acid, 6,11-dihydro-11-oxo-
- 中文名:
- 硫平酸
- 中文别名:
- 硫平酸;化合物 T17101
- CBNumber:
- CB61179929
- 分子式:
- C16H12O3S
- 分子量:
- 284.33
- MOL File:
- 61220-69-7.mol
|
|
|
硫平酸化学性质
-
沸点:
-
541.3±50.0 °C(Predicted)
-
|
-
密度:
-
1.372±0.06 g/cm3(Predicted)
-
|
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in DMSO
-
|
-
形态:
-
Solid
-
|
-
酸度系数(pKa):
-
4.14±0.10(Predicted)
-
|
-
颜色:
-
White to off-white
-
|
硫平酸性质、用途与生产工艺
体外:在DMSO中10mM 。
硫平酸是一种二苯并噻吩,是具有口服活性且高度有效的抗炎,镇痛和解热剂。
Tiopinac (0.03-110 mg/kg) has 40 times the antiphlogistic potency of phenylbutazone. The dose required to reduce paw swelling by 30% is approximately 0.5 mg/kg. Tiopinac does not elicit overt side effects at the 20 mg/kg/day dose. Tiopinac causes a dose-related reversal of the decreases body weight caused by the adjuvant disease, the weight of those rats receiving 0.135 and 0.4 mg/kg/day being significantly greater than that of the positive controls. Tiopinac (0.3-30 mg/kg) is highly potent in inhibiting the pain evoked in the yeastinflamed hind paw of the rat.
硫平酸
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
---|
2024/04/30 | HY-U00063 | 硫平酸 Tiopinac | 61220-69-7 | 1mg | 2550元 |
61220-69-7, 硫平酸 相关搜索:
- 化合物 T17101
- 硫平酸
- 61220-69-7
- RS 40974
- Dibenzo[b,e]thiepin-3-acetic acid, 6,11-dihydro-11-oxo-
- Tiopinac