PHTPP
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- CAS号:
- 805239-56-9
- 英文名:
- 4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]PHENOL
- 英文别名:
- PHTPP;4-[2-phenyl-5;5-a]pyrimidin-3-yl]phenol;7-bis(trifluoromethyl)pyrazolo[1;4-[2-PHENYL-5，7-BIS(TRIFLUOROMETHYL)PYRA...;Inhibitor,inhibit,Estrogen Receptor/ERR,PHTPP;4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]PHENOL;Phenol, 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-
- 中文名:
- PHTPP
- 中文别名:
- 化合物PHTPP;PHTPP,ERΒ拮抗剂;4-(2-苯基-5,7-双(三氟甲基)吡唑并[1,5-A]嘧啶-3-基)苯酚;4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRA...;2-苯基-3-(4-羟基苯基)-5,7-双(三氟甲基)-吡唑并[1,5-A] 嘧啶, 4-[2-苯基-5,7-双(三氟甲基)吡唑并[1,5-A]-嘧啶-3-基] 苯酚
- CBNumber:
- CB62453433
- 分子式:
- C20H11F6N3O
- 分子量:
- 423.31
- MOL File:
- 805239-56-9.mol
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PHTPP化学性质
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储存条件:
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2-8°C
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溶解度:
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DMSO : 25 mg/mL (59.06 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
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形态:
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powder
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颜色:
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yellow to orange
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PHTPP性质、用途与生产工艺
PHTPP 是一种选择性雌激素受体 β (ERβ) 拮抗剂，其选择性是 ERα 的 36 倍。
PHTPP is a selective ERβ antagonist. PHTPP reduces FSH-mediated cAMP production by 80% (p<0.01) while it has no effect on basal cAMP. PHTPP (10
-6
M) inhibits E2-stimulated ERβ activity, but does not suppress E2-stimulated ERα activity. A high dose of PHTPP (10
-6
M) slightly increases class 1
Igf1
mRNA expression, and facilitates the DPN-induced increase in class 1
Igf1
mRNA expression.
PHTPP
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下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/11/08 | HY-103456 | PHTPP | | 1 mg | 272元 |
| 2024/11/08 | HY-103456 | PHTPP
PHTPP | 805239-56-9 | 5mg | 600元 |
805239-56-9, PHTPP 相关搜索:
- 抑制剂
- 合成有机化合物配体
- 生化试剂
- C20H11F6N3O
- PHTPP,ERΒ拮抗剂
- 4-(2-苯基-5,7-双(三氟甲基)吡唑并[1,5-A]嘧啶-3-基)苯酚
- 4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRA...
- 化合物PHTPP
- 2-苯基-3-(4-羟基苯基)-5,7-双(三氟甲基)-吡唑并[1,5-A] 嘧啶, 4-[2-苯基-5,7-双(三氟甲基)吡唑并[1,5-A]-嘧啶-3-基] 苯酚
- 805239-56-9
- Inhibitor,inhibit,Estrogen Receptor/ERR,PHTPP
- 4-[2-PHENYL-5，7-BIS(TRIFLUOROMETHYL)PYRA...
- Phenol, 4-[2-phenyl-5,7-bis(trifluoromethyl)pyrazolo[1,5-a]pyrimidin-3-yl]-
- 7-bis(trifluoromethyl)pyrazolo[1
- 5-a]pyrimidin-3-yl]phenol
- 4-[2-phenyl-5
- PHTPP
- 4-[2-PHENYL-5,7-BIS(TRIFLUOROMETHYL)PYRAZOLO[1,5-A]PYRIMIDIN-3-YL]PHENOL