链球菌溶素O
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- CAS号:
- 98072-47-0
- 英文名:
- STREPTOLYSIN O
- 英文别名:
- STREPTOLYSIN O;Einecs 308-500-3;Streptococcus sp.;STREPTOLYSIN O REAGENT;STREPTOLYSIN O GAMMA-IRRADIATED;Hemolysins O, Streptococcus group A;STREPTOLYSIN O FROM STREPTOCOCCUS*PYOGEN ES;Native Streptococcus pyogenes Streptolysin O
- 中文名:
- 链球菌溶素O
- 中文别名:
- 链球菌;溶血素 O;链球菌溶素O;链球菌溶血素O;溶血素O抗原SLO;化合物 T19565;ATCC 15300 链球菌;来自化脓性链球菌的链球菌溶血素O;链球菌溶血素O 来源于化脓链球菌
- CBNumber:
- CB6407012
- 分子式:
- NULL
- 分子量:
- 0
- MOL File:
- Mol file
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链球菌溶素O化学性质
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储存条件:
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2-8°C
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溶解度:
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H2O: soluble1mg/mL
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形态:
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lyophilized powder
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颜色:
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white
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链球菌溶素O性质、用途与生产工艺
按对绵羊红细胞溶血能力可分为：①甲型(a)溶血性链球菌，又称草绿色链球菌，是人类呼吸道及肠道的正常寄居菌，致病力低。②乙型(β)溶血性链球菌，又称溶血性链球菌，致病力强，可引起人或动物多种疾病。③丙型链球菌，又称非溶血性链球菌，一般无致病性，常存在于乳品及粪便中。其中研究最多的为乙型(β)溶血性链球菌。
Streptolysin O，A组链球菌毒素，是一个氧不稳定原型胆固醇结合细菌外毒素。Streptolysin O 导致细胞裂解和心脏毒性。Streptolysin O 用于细胞膜的可控渗透性。Streptolysin O 以两种形式存在，即还原活性状态和氧化可逆不活动状态。
Streptolysin O is a labile toxin, and, with time, activity is irreversibly lost. The rate of activity loss is slowed by incubation with 0.1 M 2-mercaptoethanol or 0.01 M ethylenediaminetetraacetic acid (EDTA).
Streptolysin O, belongs to the group of thiol-activated toxins, is a secreted virulence factor of GAS that induces apoptosis in neutrophils and macrophages at later time points (~4 h). Streptolysin O induces eukaryotic cell lysis in a cholesterol-dependent manner, is highly upregulated in the GAS M1T1 clone during bloodstream dissemination. Streptolysin O is known to promote Group A Streptococcus (GAS) resistance to phagocytic clearance by neutrophils, a critical first element of host defense against invasive bacterial infection.
链球菌溶素O
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
|---|
| 2024/04/30 | HY-135416 | 链球菌溶素O
Streptolysin O | 98072-47-0 | 25KU | 5580元 |
98072-47-0, 链球菌溶素O 相关搜索:
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- 来自化脓性链球菌的链球菌溶血素O
- 链球菌溶血素O 来源于化脓链球菌
- 溶血素O抗原SLO
- 化合物 T19565
- ATCC 15300 链球菌
- 链球菌
- 链球菌溶血素O
- 溶血素 O
- 链球菌溶素O
- 98072-47-0
- Streptococcus sp.
- Native Streptococcus pyogenes Streptolysin O
- Einecs 308-500-3
- STREPTOLYSIN O FROM STREPTOCOCCUS*PYOGEN ES
- STREPTOLYSIN O GAMMA-IRRADIATED
- Hemolysins O, Streptococcus group A
- STREPTOLYSIN O REAGENT
- STREPTOLYSIN O