166882-70-8
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- CAS号:
- 166882-70-8
- 英文名:
- 2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]-
- 英文别名:
- ZD 4407;AZD 4407;2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]-
- 中文名:
- 166882-70-8
- 中文别名:
- 化合物 T10438;化合物 AZD 4407
- CBNumber:
- CB73285834
- 分子式:
- C19H21NO3S2
- 分子量:
- 375.5
- MOL File:
- 166882-70-8.mol
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166882-70-8化学性质
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沸点:
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665.6±55.0 °C(Predicted)
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密度:
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1.38±0.1 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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Soluble in DMSO
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酸度系数(pKa):
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13.68±0.40(Predicted)
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166882-70-8性质、用途与生产工艺
AZD 4407 是一种有效的 5-脂氧合酶 (5-lipoxygenase) 抑制剂。
In view of the powerful spasmogenic actions of leukotrienes in vascular and bronchial tissue, drugs which block their biosynthesis by inhibiting 5-lipoxygenase may have therapeutic potential in a variety of inflammatory conditions including inflammatory arthropothies, asthma, psoriasis, and inflammatory bowel disease. One such compound is AZD 4407 (ZD4407).
166882-70-8
上下游产品信息
上游原料
下游产品
166882-70-8, 166882-70-8 相关搜索:
- 抑制剂
- 化合物 AZD 4407
- 化合物 T10438
- 166882-70-8
- ZD 4407
- AZD 4407
- 2H-Indol-2-one,1,3-dihydro-1-methyl-5-[[4-[(2S,4R)-tetrahydro-4-hydroxy-2-methyl-2H-pyran-4-yl]-2-thienyl]thio]-