DIPROTIN A TFA
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- CAS号:
- 209248-71-5
- 英文名:
- Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))
- 英文别名:
- Diprotin A TFA;Ile-Pro-Pro (TFA);Diprotin A TFA (Ile-Pro-Pro (TFA));Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))
- 中文名:
- DIPROTIN A TFA
- 中文别名:
- 化合物 T11049;抑二肽素 A,三氟乙酸盐
- CBNumber:
- CB74844713
- 分子式:
- C19H32F3N3O6
- 分子量:
- 455.48
- MOL File:
- 209248-71-5.mol
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DIPROTIN A TFA化学性质
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储存条件:
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Store at -20°C
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形态:
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Solid
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颜色:
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White to off-white
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水溶解性:
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Water : ≥ 77.5 mg/mL (170.15 mM)
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DIPROTIN A TFA性质、用途与生产工艺
Diprotin A TFA (Ile-Pro-Ile TFA) 是二肽基肽酶 IV (DPP-IV) 的抑制剂。
Diprotin A increases the phosphorylation of Src and vascular endothelial-cadherin (VE-cadherin) in human endothelial cells and disrupts endothelial cell-to-cell junctions, which are attenuated by CXCR4 (receptor of SDF-1α)-blocker or Src-inhibitor.
In the model of retinopathy of prematurity, Diprotin A increases not only retinal vascularity but also leakage. Additionally, in the murine diabetic retinopathy model, Diprotin A increases the phosphorylation of Src and VE-cadherin and aggravates vascular leakage in the retinas. Collectively, Diprotin A induces vascular leakage by augmenting the SDF-1α/CXCR4/Src/VE-cadherin signaling pathway.
DIPROTIN A TFA
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| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/04/30 | HY-111174A | DIPROTIN A TFA
Diprotin A TFA | 209248-71-5 | 5mg | 650元 |
| 2024/04/30 | HY-111174A | DIPROTIN A TFA
Diprotin A TFA | 209248-71-5 | 10mM * 1mLin Water | 715元 |
209248-71-5, DIPROTIN A TFA 相关搜索:
- 酶
- 抑制剂
- 抑二肽素 A,三氟乙酸盐
- 化合物 T11049
- 209248-71-5
- Ile-Pro-Pro (TFA)
- Diprotin A TFA
- Diprotin A TFA (Ile-Pro-Pro (TFA))
- Diprotin A TFA (Synonyms: Ile-Pro-Pro (TFA))