化合物 T11577
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- CAS号:
- 654059-21-9
- 英文名:
- Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)
- 英文别名:
- BAY 59-9435;HSL inhibitor 2;BAY 59 9435,BAY 599435;(S)-4-Isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one;5(2H)-Isoxazolone, 3-methyl-4-(1-methylethyl)-2-[[(3S)-3-methyl-1-piperidinyl]carbonyl]-;Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)
- 中文名:
- 化合物 T11577
- 中文别名:
- 化合物 T11577
- CBNumber:
- CB81867767
- 分子式:
- C14H22N2O3
- 分子量:
- 266.34
- MOL File:
- 654059-21-9.mol
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化合物 T11577化学性质
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沸点:
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345.8±25.0 °C(Predicted)
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密度:
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1.140±0.06 g/cm3(Predicted)
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储存条件:
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Store at -20°C
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溶解度:
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DMSO: 250 mg/mL (938.65 mM)
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形态:
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Solid
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酸度系数(pKa):
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-1.21±0.40(Predicted)
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颜色:
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White to off-white
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化合物 T11577性质、用途与生产工艺
BAY 59-9435 是一种有效的、激素敏感性脂肪酶 (HSL) 的选择性抑制剂,其 IC50 值为 0.023 μM。
BAY 59-9435 significantly diminishes the isoproterenol-increased media IL-6. BAY 59-9435 blocks isoproterenol-induced SphK1 expression.
Western Blot Analysis
Cell Line:
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3T3-L1 cells.
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Concentration:
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10 μM.
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Incubation Time:
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1 h.
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Result:
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Pretreatment with BAY completely abrogated the induction of SphK1 expression by CL.
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化合物 T11577
上下游产品信息
上游原料
下游产品
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/08/19 | HY-102056 | 化合物 T11577 BAY 59-9435 | 654059-21-9 | 1mg | 1364元 |
2024/08/19 | HY-102056 | 化合物 T11577 BAY 59-9435 | 654059-21-9 | 5mg | 3000元 |
654059-21-9, 化合物 T11577 相关搜索:
- 化合物 T11577
- 654059-21-9
- BAY 59 9435,BAY 599435
- BAY 59-9435
- 5(2H)-Isoxazolone, 3-methyl-4-(1-methylethyl)-2-[[(3S)-3-methyl-1-piperidinyl]carbonyl]-
- HSL inhibitor 2
- (S)-4-Isopropyl-3-methyl-2-(3-methylpiperidine-1-carbonyl)isoxazol-5(2H)-one
- Piperidine, 3-methyl-1-[[3-methyl-4-(1-methylethyl)-5-oxo-2(5H)-isoxazolyl]carbonyl]-, (3S)- (9CI)