BETAMETHASONE HYDROCHLORIDE
|
|
|
- CAS号:
- 956901-32-9
- 英文名:
- BetaMethasone (hydrochloride)
- 英文别名:
- BetaMethasone (hydrochloride)
- 中文名:
- BETAMETHASONE HYDROCHLORIDE
- 中文别名:
- 盐酸倍他米松
- CBNumber:
- CB82677080
- 分子式:
- C28H38ClFO7
- 分子量:
- 541.0485232
- MOL File:
- 956901-32-9.mol
|
|
|
BETAMETHASONE HYDROCHLORIDE化学性质
-
储存条件:
-
Store at -20°C
-
|
-
溶解度:
-
Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc.
-
|
-
形态:
-
Powder
-
|
BETAMETHASONE HYDROCHLORIDE性质、用途与生产工艺
Betamethasone hydrochloride 是一种合成糖皮质激素，具有抗炎和免疫抑制活性。Betamethasone hydrochloride 可加速胎儿肺成熟并诱导基因表达和细胞凋亡。
Betamethasone (0.1-1 μM; 12 h) induces gene expression in L929 cells.
Betamethasone (0.1-1 μM; 48 h) induces CEM C7 T-cells apoptosis.
Betamethasone (0.48 mg; i.v.gtt for 48 h) decreases the hypercapnia-induced increase in CBF due to decreased cerebral vasodilatation.
Betamethasone (0.05 ml (1 mg/L); topical injection) ameliorates spinal nerve transection induced mechanical allodynia and thermal hyperalgesia, and reduces the activation of NF-κB and elevation of TNFα and IL-1β, and induces the expression of IL-10 in the rats brain.
|
Animal Model:
|
Rambouillet-Colombia ewes bred on a single occasion are received hypercapnic challenges
|
|
Dosage:
|
0.48 mg
|
|
Administration:
|
Injected into the fetal jugular vein at a rate of 1 ml/h (10 μg betamethasone/h) and maintained over the next 48 h.
|
|
Result:
|
Decreased cerebral blood flow (CBF) in all brain regions measured except the hippocampus after 24 h of infusion.
The reduction in CBF was diminished to about 25-30 % after 48 h of infusion.
|
BETAMETHASONE HYDROCHLORIDE
上下游产品信息
上游原料
下游产品
BETAMETHASONE HYDROCHLORIDE
生产厂家
956901-32-9, BETAMETHASONE HYDROCHLORIDE 相关搜索:
- C22H29FO5Cl
- 盐酸倍他米松
- 956901-32-9
- BetaMethasone (hydrochloride)