TYR-GLY-GLY-PHE-LEU-NH2
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- CAS号:
- 60117-24-0
- 英文名:
- LEU-ENKEPHALIN AMIDE
- 英文别名:
- YGGFL-NH2;NSC 351912;LEU-ENKEPHALIN NH2;enkephalinamide-leu;LEU-ENKEPHALIN AMIDE;[LEU5]-ENKEPHALIN AMIDE;DYNORPHIN A (1-5) AMIDE;TYR-GLY-GLY-PHE-LEU-NH2;leucine enkephalinamide;H-TYR-GLY-GLY-PHE-LEU-NH2
- 中文名:
- TYR-GLY-GLY-PHE-LEU-NH2
- 中文别名:
- 受体激动剂多肽LEU-ENKEPHALIN, AMIDE;2-[[2-[[2-[[2-[[2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]AMINO]ACETYL]AMINO]ACETYL]AMINO]-3-PHENYLPROPANOYL]AMINO]-4-METHYLPENTANAMIDE
- CBNumber:
- CB8373676
- 分子式:
- C28H38N6O6
- 分子量:
- 554.64
- MOL File:
- 60117-24-0.mol
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TYR-GLY-GLY-PHE-LEU-NH2化学性质
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熔点:
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123-126 °C
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沸点:
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1012.8±65.0 °C(Predicted)
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密度:
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1.254±0.06 g/cm3(Predicted)
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储存条件:
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−20°C
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溶解度:
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Soluble in DMSO
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形态:
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Solid
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酸度系数(pKa):
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9.97±0.15(Predicted)
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颜色:
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White to off-white
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TYR-GLY-GLY-PHE-LEU-NH2性质、用途与生产工艺
[Leu5]-Enkephalin, amide 是一种 δ 阿片受体 (opioid receptor) 激动剂。
[Leu5]-Enkephalin causes concentration-dependent, reversible inhibition of pelvic nerve-evoked contractions, with an IC
50
value of 2.1 nM.
Levels of [Leu5]-Enkephalin are significantly increased in the nucleus raphe magnus (NRM) of rats 2 weeks after the injection of complete Freund's adjuvant (CFA) (1.02±0.2 pmol/mg protein) as compared with saline-treated rats (0.49±0.04 pmol/mg protein; p<0.01). Tissue levels of [Leu5]-Enkephalin are uniformly increased in the caudal ventrolateral periaqueductal gray (PAG) 4 hr (1.15±0.25 pmol/mg protein), 4 d (1.16±0.18 pmol/mg protein), and 2 weeks (1.18±0.17 pmol/mg protein) after the injection of CFA as compared with saline-treated rats (0.55±0.03 pmol/mg protein; p<0.05, all times). A smaller increase in the levels of [Leu5]-Enkephalin occurred in the rostral aspect of the ventrolateral PAG at all time points. Finally, levels of [Leu5]-Enkephalin are also increased in the contralateral microcellular tegmental nucleus 4 d after the injection of CFA (0.53±0.04 pmol/mg protein) compared with levels in saline-treated rats (0.38±0.02 pmol/mg protein; p<0.05).
TYR-GLY-GLY-PHE-LEU-NH2
上下游产品信息
上游原料
下游产品
| 更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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| 2024/11/08 | HY-P1470 | [Leu5]-Enkephalin, amide | | 5 mg | 481元 |
| 2024/11/08 | HY-P1470 | TYR-GLY-GLY-PHE-LEU-NH2
[Leu5]-Enkephalin, amide | 60117-24-0 | 10mg | 770元 |
TYR-GLY-GLY-PHE-LEU-NH2
生产厂家
60117-24-0, TYR-GLY-GLY-PHE-LEU-NH2 相关搜索:
- Opioid Peptides
- Peptides
- Enkephalins
- BioChemical
- Amino Acids and Peptides
- Biochemicals and Reagents
- C28H38N6O6
- 受体激动剂多肽LEU-ENKEPHALIN, AMIDE
- 2-[[2-[[2-[[2-[[2-AMINO-3-(4-HYDROXYPHENYL)PROPANOYL]AMINO]ACETYL]AMINO]ACETYL]AMINO]-3-PHENYLPROPANOYL]AMINO]-4-METHYLPENTANAMIDE
- 60117-24-0
- Leu-Enkephalin amide,α-Neoendorphin (1-5) amide
- Leu-Enkephalin amide acetate salt H-Tyr-Gly-Gly-Phe-Leu-NH2 acetate salt
- NSC 351912
- L-Leucinamide, L-tyrosylglycylglycyl-L-phenylalanyl-
- Leu-Enkephalin amide acetate salt
- Leu-Enkephalin amide,α-Neoendorphin (1-5) amide
- a-Neoendorphin (1-5) aMide, Dynorphin A (1-5) aMide
- L-Tyr-Gly-Gly-L-Phe-L-Leu-NH2
- 4-Hydroxy-L-Phe-Gly-Gly-Phe-Leu-NH2
- leucine enkephalinamide
- TYR-GLY-GLY-PHE-LEU-NH2
- YGGFL-NH2
- enkephalinamide-leu
- [LEU5]-ENKEPHALIN AMIDE
- LEU-ENKEPHALIN AMIDE
- LEU-ENKEPHALIN NH2
- H-TYR-GLY-GLY-PHE-LEU-NH2 ACETATE SALT
- H-TYR-GLY-GLY-PHE-LEU-NH2
- DYNORPHIN A (1-5) AMIDE ACETATE SALT
- DYNORPHIN A (1-5) AMIDE
- leucine enkephalinamide acetate
- ALPHA-NEOENDORPHIN (1-5) AMIDE