2-PCCA(hydrochloride)
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- CAS号:
- 英文名:
- 2-PCCA(hydrochloride)
- 英文别名:
- 2-PCCA(hydrochloride)
- 中文名:
- 中文别名:
- CBNumber:
- CB85419654
- 分子式:
- C??H??Cl?N?O?
- 分子量:
- 0
- MOL File:
- Mol file
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2-PCCA(hydrochloride)化学性质
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形态:
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Solid
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颜色:
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White to light yellow
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2-PCCA(hydrochloride)性质、用途与生产工艺
2-PCCA hydrochloride 是一种外消旋体,为 GPR88 受体激动剂,在 HEK293 细胞中,可抑制 GPR88 介导的 cAMP 的产生,EC50 值为 116 nM。
EC50: 116 nM (GPR88 receptor, HEK293 cells)
2-PCCA hydrochloride inhibits GPR88-mediated cAMP production through a Gαi-coupled pathway, with an EC
50
of 116 nM in HEK293 cells stably expressing the human GPR88 receptor and the GloSensor-22F cAMP construct.
2-PCCA (0.1-3.2 mg/kg, i.p.) decreases the locomotor activity in rats in a dose-dependent manner in rats. 2-PCCA combined with 1.0 mg/kg methamphetamine also dose-dependently reduces methamphetamine-induced hyperactivity. 2-PCCA (1-3.2 mg/kg, i.p.) alone does not produce methamphetamine-like discriminative stimulus effects, or alter the discriminative stimulus effects of methamphetamine, when studied in combination.
2-PCCA(hydrochloride)
上下游产品信息
上游原料
下游产品
2-PCCA(hydrochloride) 试剂级价格
更新日期 | 产品编号 | 产品名称 | CAS编号 | 包装 | 价格 |
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2024/01/25 | HY-100013C | 2-PCCA hydrochloride | | 1 mg | 1300元 |
2024/01/25 | HY-100013C | 2-PCCA hydrochloride | | 5mg | 3200元 |
2-PCCA(hydrochloride)
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